ArticleNucleic acids research2011
BiQ Analyzer HT: locus-specific analysis of DNA methylation by high-throughput bisulfite sequencing.
Article in Nucleic acids research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
69 citing papers in PubMed.
- DNA methylation, nucleic acid structure, and rett mutations tune MeCP2 binding affinity and cooperativity.The Journal of biological chemistry · 2026Article
- Targeted DNA Methylation Editing Using an All-in-One System Establishes Paradoxical Activation ofCancers · 2024Article
- Inheritance of perturbed methylation and metabolism caused by uterine malnutrition via oocytes.BMC biology · 2023Article
- mEpigenetics · 2022Article
- A transition phase in late mouse oogenesis impacts DNA methylation of the early embryo.Communications biology · 2022Article
- Heritable Epigenomic Modifications Influence Stress Resilience and Rapid Adaptations in the Brown Planthopper (International journal of molecular sciences · 2022Article
- Epigenetic upregulation of TET2 is an independent poor prognostic factor for intrahepatic cholangiocarcinoma.Virchows Archiv : an international journal of pathology · 2022Article
- Cigarette heavy smoking alters DNA methylation patterns and gene transcription levels in humans spermatozoa.Environmental science and pollution research international · 2022Article
- Bisulfite profiling of the MGMT promoter and comparison with routine testing in glioblastoma diagnostics.Clinical epigenetics · 2022Article
- Salivary DNA methylation markers for cancer of oral cavity.Cancer biomarkers : section A of Disease markers · 2022Article
- Current and Emerging Technologies for the Analysis of the Genome-Wide and Locus-Specific DNA Methylation Patterns.Advances in experimental medicine and biology · 2022Article
- Next-Generation Bisulfite Sequencing for Targeted DNA Methylation Analysis.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Article
- DNA hypomethylation leads to cGAS-induced autoinflammation in the epidermis.The EMBO journal · 2021Article
- Hairpin-bisulfite sequencing of cells exposed to decitabine documents the process of DNA demethylation.Epigenetics · 2021Article
- Locus-Specific DNA Methylation Editing in Melanoma Cell Lines Using a CRISPR-Based System.Cancers · 2021Article
- Ten Years of EWAS.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Review
- Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR.Epigenetics & chromatin · 2021Article
- A DNA methylation-based liquid biopsy for triple-negative breast cancer.NPJ precision oncology · 2021Article
- An aging and p53 related marker:Aging · 2021Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bisulfite sequencing is a widely used method for measuring DNA methylation in eukaryotic genomes. The assay provides single-base pair resolution and, given sufficient sequencing depth, its quantitative accuracy is excellent. High-throughput sequencing of bisulfite-converted DNA can be applied either genome wide or targeted to a defined set of genomic loci (e.g. using locus-specific PCR primers or DNA capture probes). Here, we describe BiQ Analyzer HT (http://biq-analyzer-ht.bioinf.mpi-inf.mpg.de/), a user-friendly software tool that supports locus-specific analysis and visualization of high-throughput bisulfite sequencing data. The software facilitates the shift from time-consuming clonal bisulfite sequencing to the more quantitative and cost-efficient use of high-throughput sequencing for studying locus-specific DNA methylation patterns. In addition, it is useful for locus-specific visualization of genome-wide bisulfite sequencing data.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.