ArticleEndocrinology and metabolism clinics of North America2011
Cushing's syndrome: all variants, detection, and treatment.
Article in Endocrinology and metabolism clinics of North America, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 88 citations in OpenAlex.
- Updates on the role of adrenal steroidogenesis inhibitors in Cushing's syndrome: a focus on novel therapies.Pituitary · 2016Pooled it
- Identification of High-Risk Individuals for Osteoporosis and Fragility Fractures in Cushing's Syndrome: A Promising Predictive Approach.Journal of clinical medicine · 2026Article
- Severe Ectopic ACTH-Dependent Cushing Syndrome Due to a Neuroendocrine Tumor of Occult Primary Origin Presenting with Widespread Metastases and Early Vertebral Fractures: A Rare Case Report.International medical case reports journal · 2026Article
- Cedrol mitigates hepatic lipid accumulation and adipocyte hypertrophy induced by corticosteroids through the inhibition of glucocorticoid receptor activity.Scientific reports · 2025Article
- A Second Look at Cushing Disease: Hypercortisolism Recurrence From Another Gland.JCEM case reports · 2025Article
- Cushing syndrome in paediatric population: who and how to screen.Journal of endocrinological investigation · 2025Review
- Different Treatment Modalities of Oral Lichen Planus-A Narrative Review.Dentistry journal · 2023Review
- Steroid as double edged sword; a catastrophic event in the rural part of Nepal.Annals of medicine and surgery (2012) · 2022Article
- What the hippocampus tells the HPA axis: Hippocampal output attenuates acute stress responses via disynaptic inhibition of CRF+ PVN neurons.Neurobiology of stress · 2022Article
- Empagliflozin improves chronic hypercortisolism-induced abnormal myocardial structure and cardiac function in mice.Therapeutic advances in chronic disease · 2020Article
- Hypertension due to a deoxycorticosterone-secreting adrenal tumour diagnosed during pregnancy.Endocrinology, diabetes & metabolism case reports · 2019Article
- Hypokalemia associated with mifepristone use in the treatment of Cushing's syndrome.Endocrinology, diabetes & metabolism case reports · 2019Article
- Hypothalamic-Pituitary-Adrenal Hypofunction in Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS) as a Consequence of Activated Immune-Inflammatory and Oxidative and Nitrosative Pathways.Molecular neurobiology · 2017Review
- A decline in female baboon hypothalamo-pituitary-adrenal axis activity anticipates aging.Aging · 2017Article
- Severe Cushing's syndrome and bilateral pulmonary nodules: beyond ectopic ACTH.Endocrinology, diabetes & metabolism case reports · 2017Article
- Management of Cushing syndrome in children and adolescents: experience of a single tertiary centre.European journal of pediatrics · 2016Article
- Choroidal and Retinal Abnormalities by Optical Coherence Tomography in Endogenous Cushing's Syndrome.Frontiers in endocrinology · 2016Article
- Cushing's syndrome: epidemiology and developments in disease management.Clinical epidemiology · 2015Review
- Physiological basis for the etiology, diagnosis, and treatment of adrenal disorders: Cushing's syndrome, adrenal insufficiency, and congenital adrenal hyperplasia.Comprehensive Physiology · 2014Review
- Inhalational Steroids and Iatrogenic Cushing's Syndrome.The open respiratory medicine journal · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Diagnosis of Cushing's syndrome involves a step-wise approach and establishing the cause can be challenging. Several pathogenic mechanisms have been proposed for glucocorticoid-induced hypertension, including a functional mineralocorticoid excess state, upregulation of the renin angiotensin system, and deleterious effects of cortisol on the vasculature. Surgical excision of the cause of excess glucocorticoids remains the optimal treatment. Antiglucocorticoid and antihypertensive agents and steroidogenesis inhibitors can be used as adjunctive treatment modalities in preparation for surgery and in cases where surgery is contraindicated or has not led to cure.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.