Trial reportBehaviour research and therapy2011
A cognitive-behavioral treatment for irritable bowel syndrome using interoceptive exposure to visceral sensations.
Trial report in Behaviour research and therapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00368771 (A Six-Month Study to Compare Outcome Differences and Visceral Response in Subjects Randomized to a Psychological Intervention for Irritable Bowel Syndrome), which is not on this map. Cited by 94 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Six-Month Study to Compare Outcome Differences and Visceral Response in Subjects Randomized to a Psychological Intervention for Irritable Bowel Syndrome
Who cites it
94 citing papers in PubMed, 6 syntheses or guidelines pooled it, 244 citations in OpenAlex.
- European Consensus on Functional Bloating and Abdominal Distension-An ESNM/UEG Recommendations for Clinical Management.United European gastroenterology journal · 2025Guideline
- Psychological interventions for interoception in mental health disorders: A systematic review of randomized-controlled trials.Psychiatry and clinical neurosciences · 2023Pooled it
- Pooled it
- Potential Benefit With Complementary and Alternative Medicine in Irritable Bowel Syndrome: A Systematic Review and Meta-analysis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2021Pooled it
- Systematic review: The placebo effect of psychological interventions in the treatment of irritable bowel syndrome.World journal of gastroenterology · 2017Pooled it
- Irritable bowel syndrome.BMJ clinical evidence · 2012Pooled it
- The Effects of Cognitive Behavioral Therapy for Insomnia among College Students with Irritable Bowel Syndrome: A Randomized Controlled Trial.International journal of environmental research and public health · 2022Trial
- Return on investment of internet delivered exposure therapy for irritable bowel syndrome: a randomized controlled trial.BMC gastroenterology · 2021Trial
- Efficacy of Zemedy, a Mobile Digital Therapeutic for the Self-management of Irritable Bowel Syndrome: Crossover Randomized Controlled Trial.JMIR mHealth and uHealth · 2021Trial
- Written expressive disclosure in adults with irritable bowel syndrome: A randomized controlled trial.Complementary therapies in clinical practice · 2021Trial
- Cost-effectiveness of internet-delivered cognitive-behavioural therapy for adolescents with irritable bowel syndrome.BMJ open · 2019Trial
- Internet-Delivered Cognitive Behavior Therapy for Adolescents With Irritable Bowel Syndrome: A Randomized Controlled Trial.The American journal of gastroenterology · 2017Trial
- Modifying resilience mechanisms in at-risk individuals: a controlled study of mindfulness training in Marines preparing for deployment.The American journal of psychiatry · 2014Trial
- Trial
- Prediction of symptomatic improvement after exposure-based treatment for irritable bowel syndrome.BMC gastroenterology · 2013Trial
- Randomised clinical trial: symptoms of the irritable bowel syndrome are improved by a psycho-education group intervention.Alimentary pharmacology & therapeutics · 2013Trial
- Therapeutic mechanisms of a mindfulness-based treatment for IBS: effects on visceral sensitivity, catastrophizing, and affective processing of pain sensations.Journal of behavioral medicine · 2012Trial
- Visceral sensitivity as a mediator of outcome in the treatment of irritable bowel syndrome.Behaviour research and therapy · 2012Trial
- Acceptability, effectiveness, and cost-effectiveness of internet-based exposure treatment for irritable bowel syndrome in a clinical sample: a randomized controlled trial.BMC gastroenterology · 2011Trial
- A Novel Application of Inhibitory Learning Theory: Pediatric Retentive Encopresis.Clinical child and family psychology review · 2026Article
34 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
backgroundIrritable bowel syndrome (IBS) is a chronic and debilitating medical condition with few efficacious pharmacological or psychosocial treatment options available. Evidence suggests that visceral anxiety may be implicated in IBS onset and severity. Thus, cognitive-behavioral treatment (CBT) that targets visceral anxiety may alleviate IBS symptoms.
methodsThe current study examined the efficacy of a CBT protocol for the treatment of IBS which directly targeted visceral sensations. Participants (N = 110) were randomized to receive 10 sessions of either: (a) CBT with interoceptive exposure (IE) to visceral sensations; (b) stress management (SM); or (c) an attention control (AC), and were assessed at baseline, mid-treatment, post-treatment, and follow-up sessions.
resultsConsistent with hypotheses, the IE group outperformed AC on several indices of outcome, and outperformed SM in some domains. No differences were observed between SM and AC. The results suggest that IE may be a particularly efficacious treatment for IBS.
conclusionsImplications for research and clinical practice are discussed.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.