ArticleInternational journal of colorectal disease2011
Overall survival after resection for colon cancer in a national cohort study was adversely affected by TNM stage, lymph node ratio, gender, and old age.
Article in International journal of colorectal disease, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Safety and Oncological Outcomes of Laparoscopic NOSE Surgery Compared With Conventional Laparoscopic Surgery for Colorectal Diseases: A Meta-Analysis.Frontiers in oncology · 2019Pooled it
- Prognostic influences of lymph node ratio in major cancers of Taiwan: a longitudinal study from a single cancer center.Journal of cancer research and clinical oncology · 2015Trial
- The effects of socioeconomic deprivation on colorectal cancer outcomes; a retrospective regional cohort study.International journal of colorectal disease · 2026Article
- Development and validation of a dynamic nomogram for individualized prediction of survival in patients with colon cancer.Scientific reports · 2024Article
- A two-phase approach to re-calibrating expensive computer simulation for sex-specific colorectal neoplasia development modeling.BMC medical informatics and decision making · 2022Article
- Are there sex differences among colorectal cancer patients in treatment and survival? A Swiss cohort study.Journal of cancer research and clinical oncology · 2021Article
- Factors related to mortality due to progression of disease in patients with colon cancer in the presence of competing risks: a retrospective cohort study in the west of Iran.Gastroenterology and hepatology from bed to bench · 2021Article
- Specific causes of recurrence after surgery and mortality in patients with colorectal cancer: A competing risks survival analysis.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2021Article
- Low Socioeconomic Status Is Associated with Worse Outcomes After Curative Surgery for Colorectal Cancer: Results from a Large, Multicenter Study.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020Article
- Joint effect of pre-operative anemia and perioperative blood transfusion on outcomes of colon-cancer patients undergoing colectomy.Gastroenterology report · 2020Article
- Comparison of a Five-Year Survival and Cancer Recurrence between Laparoscopically Assisted and Open Colonic Resections due to Adenocarcinoma-a Single Centre Experience.Medicina (Kaunas, Lithuania) · 2020Article
- A competing-risk nomogram to predict cause-specific death in elderly patients with colorectal cancer after surgery (especially for colon cancer).World journal of surgical oncology · 2020Article
- Tailored Treatment of Colorectal Cancer: Surgical, Molecular, and Genetic Considerations.Clinical Medicine Insights. Oncology · 2017Review
- Leveraging the power of pooled data for cancer outcomes research.Chinese journal of cancer · 2016Article
- Impact of tumor location on lymph node metastasis in T1 colorectal cancer.Langenbeck's archives of surgery · 2016Article
- Assessment of lymph node involvement in colorectal cancer.World journal of gastrointestinal surgery · 2016Review
- Combined assays for serum carcinoembryonic antigen and microRNA-17-3p offer improved diagnostic potential for stage I/II colon cancer.Molecular and clinical oncology · 2015Article
- Expression of ITGB1 predicts prognosis in colorectal cancer: a large prospective study based on tissue microarray.International journal of clinical and experimental pathology · 2015Article
- Incidence, clinical features and possible etiology of early onset (≤40 years) colorectal neoplasms.Internal and emergency medicine · 2014Article
- Short term results of complete (D3) vs. standard (D2) mesenteric excision in colon cancer shows improved outcome of complete mesenteric excision in patients with TNM stages I-II.Techniques in coloproctology · 2014Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA national surveillance program of colon cancer treatment was introduced in 2007. We examined prognostic factors for colon cancer operated in 2000 with an aim of improving survival in the new program and a special focus on the merit of lymph node yield.
methodsA cohort of 269 patients, 152 women (56.5%), with a mean age of 71 years, was operated for colon cancer in 2000 at three teaching hospitals and followed up for 7 years.
resultsOverall 5-year survival was 58.0%, and overall hospital mortality was 5.2%, with 4.5% in elective cases and 12.5% after urgent surgery. In only 41.1% of the specimens were 12 or more lymph nodes retrieved, but this did not affect survival in the combined cohort, although one of the hospitals achieved a significantly better result with a harvest of 12 or more lymph nodes. In a multivariate analysis, old age, gender, a high lymph node ratio (LNR) at stage III, and tumor-node-metastasis stage were adverse factors for survival.
conclusionsThe operative mortality was high and should be reassessed. The lymph node count did not have a significant impact on outcome overall, whereas the LNR proved significant for stage III. A prospective protocol using overall lymph node yield as a surrogate measure for more radical surgery, nevertheless, seems warranted to improve the lymph node harvest according to international recommendations.
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