ReviewIndian journal of gastroenterology : official journal of the Indian Society of Gastroenterology2011
Genetic factors in the pathogenesis of gastroesophageal reflux disease.
Review in Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 16 citations in OpenAlex.
- Metabolic dysfunction-associated steatotic liver disease and gastroesophageal reflux disease: a mendelian randomization study in European and East Asian populations.Frontiers in genetics · 2024Article
- Interleukin-1A and interleukin-1B gene polymorphisms in gastroesophageal reflux disease.Experimental and therapeutic medicine · 2020Article
- Risk factors for gastroesophageal reflux disease and analysis of genetic contributors.World journal of clinical cases · 2018Review
- Incidence of gastroesophageal reflux disease in Uygur and Han Chinese adults in Urumqi.World journal of gastroenterology · 2012Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
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Abstract
Multiple factors play a role in the pathogenesis of gastroesophageal reflux disease (GERD). Two landmark studies showing higher concordance of disease in monozygotic than dizygotic twin pairs suggested the role of host genetic factors in its pathogenesis. Recent studies have shown that genetic polymorphism in genes influencing host's inflammatory response, drug metabolism, cell cycle regulation, xenobiotic pathways, DNA repair, mutagenesis, esophageal sensory function and gene silencing are associated with risk of GERD and its sequelae-Barrett's esophagus and esophageal adenocarcinoma. However, more studies on larger sample size are needed before reaching a definite conclusion on the role of an individual gene.
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