ArticleThe ISME journal2011
Transcriptome response of high- and low-light-adapted Prochlorococcus strains to changing iron availability.
Article in The ISME journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
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Who cites it
65 citing papers in PubMed, 124 citations in OpenAlex.
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- Extracellular vesicles are the main contributor to the non-viral protected extracellular sequence space.ISME communications · 2023Article
- Synechococcus nitrogen gene loss in iron-limited ocean regions.ISME communications · 2023Article
- A Reduction of Transcriptional Regulation in Aquatic Oligotrophic Microorganisms Enhances Fitness in Nutrient-Poor Environments.Microbiology and molecular biology reviews : MMBR · 2023Review
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- Divergent functions of two clades of flavodoxin in diatoms mitigate oxidative stress and iron limitation.eLife · 2023Article
- Biological and Genomic Characteristics of MaMV-DH01, a Novel FreshwaterMicrobiology spectrum · 2023Article
- Diversity and Evolution of Iron Uptake Pathways in Marine Cyanobacteria from the Perspective of the Coastal StrainApplied and environmental microbiology · 2023Article
- Protist impacts on marine cyanovirocell metabolism.ISME communications · 2022Article
- Bioavailable iron titrations reveal oceanic Synechococcus ecotypes optimized for different iron availabilities.ISME communications · 2022Article
- Viruses affect picocyanobacterial abundance and biogeography in the North Pacific Ocean.Nature microbiology · 2022Article
- Exploring the Diversity of the Thioredoxin Systems in Cyanobacteria.Antioxidants (Basel, Switzerland) · 2022Review
- Acclimation and stress response ofFrontiers in microbiology · 2022Article
- Functional characterisation of substrate-binding proteins to address nutrient uptake in marine picocyanobacteria.Biochemical Society transactions · 2021Review
- A Novel Jumbo Phage PhiMa05 Inhibits HarmfulFrontiers in microbiology · 2021Article
- From the Ocean to the Lab-Assessing Iron Limitation in Cyanobacteria: An Interface Paper.Microorganisms · 2020Review
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- A framework for the computational prediction and analysis of non-coding RNAs in microbial environmental populations and their experimental validation.The ISME journal · 2020Article
5 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Prochlorococcus contributes significantly to ocean primary productivity. The link between primary productivity and iron in specific ocean regions is well established and iron limitation of Prochlorococcus cell division rates in these regions has been shown. However, the extent of ecotypic variation in iron metabolism among Prochlorococcus and the molecular basis for differences is not understood. Here, we examine the growth and transcriptional response of Prochlorococcus strains, MED4 and MIT9313, to changing iron concentrations. During steady state, MIT9313 sustains growth at an order-of-magnitude lower iron concentration than MED4. To explore this difference, we measured the whole-genome transcriptional response of each strain to abrupt iron starvation and rescue. Only four of the 1159 orthologs of MED4 and MIT9313 were differentially expressed in response to iron in both strains. However, in each strain, the expression of over a hundred additional genes changed, many of which are in labile genomic regions, suggesting a role for lateral gene transfer in establishing diversity of iron metabolism among Prochlorococcus. Furthermore, we found that MED4 lacks three genes near the iron-deficiency-induced gene (idiA) that are present and induced by iron stress in MIT9313. These genes are interesting targets for studying the adaptation of natural Prochlorococcus assemblages to local iron conditions as they show more diversity than other genomic regions in environmental metagenomic databases.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.