ArticleNature2011
Discovery of novel intermediate forms redefines the fungal tree of life.
Article in Nature, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 135 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
135 citing papers in PubMed, 1 synthesis or guideline pooled it, 421 citations in OpenAlex.
- Effects of oxygen availability on mycobenthic communities of marine coastal sediments.Scientific reports · 2023Pooled it
- Comprehensive analysis of small GTPases in Microsporidia reveals new extremes in eukaryotic cell biology.BMC biology · 2026Article
- Spatiotemporal Dynamics and Co-Occurrence Patterns of Marine Fungal Communities Along Nutrient Gradients in the Leizhou Peninsula, China.Journal of fungi (Basel, Switzerland) · 2026Article
- Size-fractionated fungal communities in the sunlit ocean.Communications biology · 2025Article
- A genomic perspective on fungal diversity and evolution.Nature reviews. Microbiology · 2025Review
- Niche formation of Rozellomycota in wastewater treatment model reactors.Scientific reports · 2025Article
- Taxonomic quasi-primes: peptides charting lineage-specific adaptations and disease-relevant loci.Protein science : a publication of the Protein Society · 2025Article
- Facilitation in the Dry Season: Species Interactions Between a Limestone-Endemic Plant and Moss Altered by Precipitation Dynamics.Plants (Basel, Switzerland) · 2025Article
- Benzofuran Derivatives with Antimicrobial and Anti-Inflammatory Activities fromInternational journal of molecular sciences · 2025Article
- The Fungal Kingdom as a Rosetta Stone for biological discovery.Current biology : CB · 2025Article
- Unraveling diversity by isolating peptide sequences specific to distinct taxonomic groups.bioRxiv : the preprint server for biology · 2025Article
- Mechanisms Driving Seasonal Succession and Community Assembly in Sediment Microbial Communities Across the Dali River Basin, the Loess Plateau, China.Microorganisms · 2025Article
- Candidatus Desulforudis audaxviator dominates a 975 m deep groundwater community in central Sweden.Communications biology · 2024Article
- Quantification of the dark fungal taxon Cryptomycota using qPCR.Environmental microbiology reports · 2024Article
- Integrated management of fruit trees andFrontiers in microbiology · 2024Article
- Single-cell genomics reveals new rozellid lineages and supports their sister relationship to Microsporidia.Biology letters · 2023Article
- The Unicellular, Parasitic Fungi, Sanchytriomycota, Possess a DNA Sequence Possibly Encoding a Long Tubulin Polymerization Promoting Protein (TPPP) but Not a Fungal-Type One.Microorganisms · 2023Article
- Genomes of fungi and relatives reveal delayed loss of ancestral gene families and evolution of key fungal traits.Nature ecology & evolution · 2023Article
- Intercomparison of Two Fluorescent Dyes to Visualize Parasitic Fungi (Chytridiomycota) on Phytoplankton.Microbial ecology · 2023Article
- DNA extraction bias is more pronounced for microbial eukaryotes than for prokaryotes.MicrobiologyOpen · 2022Article
75 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fungi are the principal degraders of biomass in terrestrial ecosystems and establish important interactions with plants and animals. However, our current understanding of fungal evolutionary diversity is incomplete and is based upon species amenable to growth in culture. These culturable fungi are typically yeast or filamentous forms, bound by a rigid cell wall rich in chitin. Evolution of this body plan was thought critical for the success of the Fungi, enabling them to adapt to heterogeneous habitats and live by osmotrophy: extracellular digestion followed by nutrient uptake. Here we investigate the ecology and cell biology of a previously undescribed and highly diverse form of eukaryotic life that branches with the Fungi, using environmental DNA analyses combined with fluorescent detection via DNA probes. This clade is present in numerous ecosystems including soil, freshwater and aquatic sediments. Phylogenetic analyses using multiple ribosomal RNA genes place this clade with Rozella, the putative primary branch of the fungal kingdom. Tyramide signal amplification coupled with group-specific fluorescence in situ hybridization reveals that the target cells are small eukaryotes of 3-5 μm in length, capable of forming a microtubule-based flagellum. Co-staining with cell wall markers demonstrates that representatives from the clade do not produce a chitin-rich cell wall during any of the life cycle stages observed and therefore do not conform to the standard fungal body plan. We name this highly diverse clade the cryptomycota in anticipation of formal classification.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.