Evidence map›Paper›PMID 21562116›Full record

ArticleClinical and vaccine immunology : CVI2011

Performance of the BioPlex 2200 multiplexing immunoassay platform for the detection of herpes simplex virus type 2 specific antibodies in African settings.

Jérôme LeGoff, Gérard Grésenguet, Chrysostome Gody, Jean De Dieu Longo, Nzambi Khonde, Helen A Weiss, Philippe Mayaud, Laurent Bélec, ANRS 12-12 Study Group

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jérôme LeGoffUniversité Paris Diderot, Sorbonne Paris Cité, Inserm U941, and Laboratoire de Virologie, Hôpital Saint-Louis, APHP, Paris, France. jerome.le-goff@sls.aphp.fr
Gérard Grésenguet
Chrysostome Gody
Jean De Dieu Longo
Nzambi Khonde
Helen A Weiss
Philippe Mayaud
Laurent Bélec
ANRS 12-12 Study Group

Funding

Medical Research Council G0700837
6 · The paper itself

Abstract

The BioPlex platform was evaluated for the detection of herpes simplex virus 2 (HSV-2) antibodies in sub-Saharan Africa individuals in comparison to clinicovirological standards and compared to HerpeSelect. The sensitivities and specificities were, respectively, 88.9% and 93.5% for BioPlex and 89.9% and 92.7% for HerpeSelect. The agreement between both assays was 95.7%.

Indexed as

Africa South of the SaharaAntibodies, ViralHerpesvirus 2, HumanHumansImmunoassaySensitivity and SpecificityAntibodies, Viral

Identifiers

PMID21562116
PMCPMC3147317

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.