ArticleJournal of clinical microbiology2011
Isolation of Mycobacterium tuberculosis strains with a silent mutation in rpoB leading to potential misassignment of resistance category.
Article in Journal of clinical microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Phenotypic discordance in rifampicin resistance detection amongMicrobiology spectrum · 2026Review
- A novel one-tube nested fluorescence melting curve analysis for rapid detection of drug-resistant Mycobacterium tuberculosis.BMC microbiology · 2025Article
- Limitations of the MTB/RIF Assay: An Xpert Review of 4 Clinical Cases.Open forum infectious diseases · 2025Article
- Microbial cell-free DNA-sequencing as an addition to conventional diagnostics in neonatal sepsis.Pediatric research · 2025Article
- Culture-Free Whole Genome Sequencing ofOpen forum infectious diseases · 2024Article
- Discordance between genotypic and phenotypic methods for the detection of rifampicin and isoniazid resistantJournal of clinical tuberculosis and other mycobacterial diseases · 2024Article
- Performance of metagenomic Next-Generation Sequencing and metagenomic Nanopore Sequencing for the diagnosis of tuberculosis in HIV-positive patients.Frontiers in cellular and infection microbiology · 2024Article
- Phenotypic drug susceptibility characterization and clinical outcomes of tuberculosis strains with A-probe mutation by GeneXpert MTB/RIF.BMC infectious diseases · 2023Article
- New developments in tuberculosis diagnosis and treatment.Breathe (Sheffield, England) · 2022Review
- Drug sensitivity of clinical isolates ofFrontiers in public health · 2022Article
- Molecular characterization of rpoB gene mutations in isolates from tuberculosis patients in Cubal, Republic of Angola.BMC infectious diseases · 2021Article
- Low-Level Rifampin Resistance andJournal of clinical microbiology · 2021Article
- Light Forge: A Microfluidic DNA Melting-based Tuberculosis Test.The journal of applied laboratory medicine · 2020Article
- Artificial Intelligence and Machine learning based prediction of resistant and susceptible mutations in Mycobacterium tuberculosis.Scientific reports · 2020Article
- Innovations in tuberculosis diagnostics: How far are we from reaching our goal?The Indian journal of medical research · 2019Article
- Xpert MTB/RIF performance to diagnose tuberculosis and rifampicin resistance in a reference centre in southern Brazil.ERJ open research · 2019Article
- Occurrence of disputed rpoB mutations among Mycobacterium tuberculosis isolates phenotypically susceptible to rifampicin in a country with a low incidence of multidrug-resistant tuberculosis.BMC infectious diseases · 2019Article
- Drug-resistant tuberculosis: challenges and opportunities for diagnosis and treatment.Current opinion in pharmacology · 2018Review
- Diagnosis of rifampicin-resistant tuberculosis: Discordant results by diagnostic methods.African journal of laboratory medicine · 2018Article
- Phenotypic and genotypic drug sensitivity ofInfection and drug resistance · 2018Article
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7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Our study provides an alert regarding the transmission of rifampin-susceptible strains of Mycobacterium tuberculosis with a silent substitution in codon 514 of rpoB. Among 1,450 cases, we identified 12 isolates sharing this mutation and related restriction fragment length polymorphism (RFLP) types. The mutation impaired hybridization with the wild-type probes in three independent commercial assays, which could lead to misassignment of resistance.
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