Evidence map›Paper›PMID 21561991›Full record

SynthesisAmerican journal of Alzheimer's disease and other dementias2011

A review of the methods used to estimate the cost of Alzheimer's disease in the United States.

Josephine Mauskopf, Lisa Mucha

Abstract readSystematic Review
In one paragraph

Synthesis in American journal of Alzheimer's disease and other dementias, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. How relevant are social costs in economic evaluations? The case of Alzheimer's disease.The European journal of health economics : HEPAC : health economics in prevention and care · 2019
    Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Review
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  8. Review
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  10. Article
  11. Road to the nursing home: costs and disease progression among medicare beneficiaries with ADRD.American journal of Alzheimer's disease and other dementias · 2012
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Josephine MauskopfHealth Economics, RTI Health Solutions, Research Triangle Park, NC, USA. jmauskopf@rti.org
Lisa Mucha

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledBACKGROUN/RATIONALE: To determine the suitability of published estimates of the US cost of Alzheimer's disease (AD) for use in cost-effectiveness models for new AD treatments.

methodsA systematic literature review of published information on direct medical, direct nonmedical, indirect, and informal care costs for different levels of disease severity.

resultsNineteen studies were included in the review. In studies presenting mean costs by disease severity, the change in different types of costs with increasing disease severity varied, depending on the data sources and characteristics of patients with AD. In studies presenting the results of regression analyses, costs were shown to be independently associated with cognition, functional status, behavioral symptoms, and dependence.

conclusionsPublished US studies (1) did not include all the types of costs and AD populations, and (2) generally did not include all the measures of disease severity that are needed for cost-effectiveness models.

Indexed as

Alzheimer DiseaseCost-Benefit AnalysisDatabases, BibliographicHumansMEDLINESeverity of Illness IndexUnited States

Identifiers

PMID21561991
PMCPMC10845619

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.