Evidence map›Paper›PMID 21561755›Full record

ReviewCurrent opinion in cell biology2011

Extracellular matrix receptors in branched organs.

Ambra Pozzi, Roy Zent

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in cell biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. The laminin binding α3 and α6 integrins cooperate to promote epithelial cell adhesion and growth.Matrix biology : journal of the International Society for Matrix Biology · 2019
    Article
  12. Review
  13. Review
  14. Integrin alpha6 maintains the structural integrity of the kidney collecting system.Matrix biology : journal of the International Society for Matrix Biology · 2017
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ambra PozziDivision of Nephrology, Department of Medicine, Vanderbilt University Medical Center and Veterans Affairs Hospital, Nashville, TN 37232, USA.
Roy Zent
Vanderbilt University Medical Center · US

Funding

TYPE IV COLLAGEN, LAMININS, AND INTEGRINS IN NORMAL AND DISEASED GLOMERULIP01DK065123 · NIDDK · VANDERBILT UNIVERSITY · PI HUDSON, BILLY GERALD · 2003 to 2012
$12.9M
The Laminin Receptors in Kidney FibrosisR01DK069921 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ROY ZENT · 2005 to 2026
$9.5M
Vanderbilt O'Brien Mouse Kidney Physiology and Disease CenterP30DK079341 · NIDDK · VANDERBILT UNIVERSITY · PI HARRIS, RAYMOND C. · 2008 to 2013
$4.4M
Betal Integrin and Renal TubulogenesisR01DK075594 · NIDDK · VANDERBILT UNIVERSITY · PI ZENT, ROY · 2008 to 2015
$2.6M
Structure Function Analysis of Integrins alpha1beta1 and alpha2beta2R01DK083187 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SANDERS, CHARLES R, ZENT, ROY · 2010 to 2013
$1.3M
NIDDK NIH HHS 2P01DK065123NIDDK NIH HHS DK075594NIDDK NIH HHS DK083187NIDDK NIH HHS DK65123NIDDK NIH HHS P01 DK065123NIDDK NIH HHS P30 DK079341NIDDK NIH HHS P30DK79341-01NIDDK NIH HHS R01 DK069921NIDDK NIH HHS R01 DK075594NIDDK NIH HHS R01 DK083187
6 · The paper itself

Abstract

Organ branching morphogenesis is a complex process that requires many coordinated cell functions, including cell migration, proliferation, and polarization. This process is regulated at numerous levels, including spatial and temporal expression of transcription factors and their regulators; growth factors and their receptors; as well as cell-cell and cell-extracellular matrix interactions. Integrins and dystroglycan are transmembrane receptors that control both the adhesion of cells to matrix components as well as transduction of signaling coming from and directed to the matrix. In this article we review current advances defining the roles of these receptors in branching morphogenesis focusing on the major epithelial cell derived structures in mammals, namely salivary gland, mammary gland, lung, pancreas, and kidney.

Indexed as

OrganogenesisAnimalsCell MovementDystroglycansEpitheliumExtracellular Matrix ProteinsGene Expression Regulation, DevelopmentalHumansIntegrinsSignal TransductionDystroglycansExtracellular Matrix ProteinsIntegrins

Identifiers

PMID21561755
PMCPMC3181278
OpenAlexW2005333479

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.