Evidence map›Paper›PMID 21559817›Full record

ReviewReviews in endocrine & metabolic disorders2011

Update on hormonal contraception and bone density.

Michelle M Isley, Andrew M Kaunitz

Abstract readReview
PubMed Publisher
In one paragraph

Review in Reviews in endocrine & metabolic disorders, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Oral contraceptive use and fracture risk-a retrospective study of 12,970 women in the UK.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017
    Article
  7. Review
  8. Review
  9. Abnormal uterine bleeding: Taking the stress out of controlling the flow.Canadian family physician Medecin de famille canadien · 2015
    Article
  10. Article
  11. Article
  12. Article
  13. Menstrual suppression: current perspectives.International journal of women's health · 2014
    Review
  14. Bone health in children and adolescents with perinatal HIV infection.Journal of the International AIDS Society · 2013
    Review
  15. Contraception in women over 40 years of age.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2013
    Review
  16. Half a century of the oral contraceptive pill: historical review and view to the future.Canadian family physician Medecin de famille canadien · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Michelle M IsleyDepartment of Obstetrics and Gynecology, The Ohio State University, Columbus, USA. Michelle.Isley@osumc.edu
Andrew M Kaunitz
Florida College · USThe Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Combination hormonal contraception and progestin-only contraception (including depot medroxyprogesterone acetate [DMPA]) are effective and convenient forms of reversible contraception that millions of women use worldwide. In recent years, observations of reduced bone mineral density in current users of these methods have led to concerns that this hormone-induced bone loss might translate into long-term increased fracture risk. Special focus has been placed on adolescent users who have not yet attained their peak bone mass as well as perimenopausal users. In 2004, the FDA added a black box warning to DMPA package labeling warning of the risk of significant bone loss and cautioning against long-term use (> 2 years). This article reviews evidence on the use of hormonal contraception and its effect on bone density in adolescent, premenopausal, and perimenopausal populations. Recommendations from reproductive healthcare organizations are reviewed and clinical recommendations are provided.

Indexed as

AdolescentAdultBone DensityContraceptive Agents, FemaleContraceptives, Oral, CombinedContraceptives, Oral, HormonalFemaleFractures, BoneHumansLactationPerimenopausePractice Guidelines as TopicRisk FactorsYoung AdultContraceptive Agents, FemaleContraceptives, Oral, CombinedContraceptives, Oral, Hormonal

Identifiers

PMID21559817
OpenAlexW1986855906

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.