Trial reportPsychopharmacology2011
Alcohol impairs brain reactivity to explicit loss feedback.
Trial report in Psychopharmacology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Alcohol and Neural Dynamics: A Meta-analysis of Acute Alcohol Effects on Event-Related Brain Potentials.Biological psychiatry · 2021Pooled it
- Moderating effect of working memory capacity on acute alcohol effects on BOLD response during inhibition and error monitoring in male heavy drinkers.Psychopharmacology · 2015Trial
- Distinct Neural Dynamics Underlying Reward Expectation Formation and Outcome Processing: Insights From ERP and Time-Frequency Analyses.Psychophysiology · 2026Article
- The complex nature of agency attribution: Neurophysiological signatures associated to monitoring self vs. external erroneous actions.iScience · 2026Article
- Risk-Taking Is Associated with Decreased Subjective Value Signals and Increased Prediction Error Signals in the Hot Columbia Card Task.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Machine learning reveals differential effects of depression and anxiety on reward and punishment processing.Scientific reports · 2024Article
- Preliminary evidence that individuals with remitted alcohol use disorder and major depressive disorder exhibit enhanced neural responses to reward: An EEG study.Addictive behaviors · 2023Article
- Sequential gains and losses during gambling feedback: Differential effects in time-frequency delta and theta measures.Psychophysiology · 2022Article
- Behavioral and electrocortical effects of transcranial alternating current stimulation during advice-guided decision-making.Neuroimage. Reports · 2021Article
- Understanding ethanol's acute effects on medial prefrontal cortex neural activity using state-space approaches.Neuropharmacology · 2021Review
- Exploring a sustainable building's impact on occupant mental health and cognitive function in a virtual environment.Scientific reports · 2021Article
- Cannabis users demonstrate enhanced neural reactivity to reward: An event-related potential and time-frequency EEG study.Addictive behaviors · 2021Article
- Acute effects of alcohol on error-elicited negative affect during a cognitive control task.Psychopharmacology · 2020Article
- An Event-Related Potential Study of Decision-Making and Feedback Utilization in Female College Students Who Binge Drink.Frontiers in psychology · 2019Article
- Effects of reward context on feedback processing as indexed by time-frequency analysis.Psychophysiology · 2018Article
- Event-Related Potentials in Relation to Risk-Taking: A Systematic Review.Frontiers in behavioral neuroscience · 2018Article
- Time-Frequency Reward-Related Delta Prospectively Predicts the Development of Adolescent-Onset Depression.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2018Article
- Feedback-Related Electroencephalogram Oscillations of Athletes With High and Low Sports Anxiety.Frontiers in psychology · 2018Article
- Expectancy effects in feedback processing are explained primarily by time-frequency delta not theta.Biological psychology · 2017Article
- Web addiction in the brain: Cortical oscillations, autonomic activity, and behavioral measures.Journal of behavioral addictions · 2017Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
rationaleAlcohol impairs the brain's detection of performance errors as evidenced by attenuated error-related negativity (ERN), an event-related potential (ERP) thought to reflect a brain system that monitors one's behavior. However, it remains unclear whether alcohol impairs performance-monitoring capacity across a broader range of contexts, including those entailing external feedback.
objectiveThis study sought to determine whether alcohol-related monitoring deficits are specific to internal recognition of errors (reflected by the ERN) or occur also in external cuing contexts. We evaluated the impact of alcohol consumption on the feedback-related negativity (FRN), an ERP thought to engage a similar process as the ERN but elicited by negative performance feedback in the environment.
methodsIn an undergraduate sample randomly assigned to drink alcohol (n = 37; average peak BAC = 0.087 g/100 ml, estimated from breath alcohol sampling) or placebo beverages (n = 42), ERP responses to gain and loss feedback were measured during a two-choice gambling task. Time-frequency analysis was used to parse the overlapping theta-FRN and delta-P3 and clarified the effects of alcohol on the measures.
resultsAlcohol intoxication attenuated both the theta-FRN and delta-P3 brain responses to feedback. The theta-FRN attenuation was stronger following loss than gain feedback.
conclusionsAttenuation of both theta-FRN and delta-P3 components indicates that alcohol pervasively attenuates the brain's response to feedback in this task. That theta-FRN attenuation was stronger following loss trials is consistent with prior ERN findings and suggests that alcohol broadly impairs the brain's recognition of negative performance outcomes across differing contexts.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.