ArticleImmunogenetics2011
Characterization of MHC-I in the blue tit (Cyanistes caeruleus) reveals low levels of genetic diversity and trans-population evolution across European populations.
Article in Immunogenetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Understanding the evolution of immune genes in jawed vertebrates.Journal of evolutionary biology · 2023Review
- Not all birds have a single dominantly expressed MHC-I gene: Transcription suggests that siskins have many highly expressed MHC-I genes.Scientific reports · 2019Article
- A quantitative and qualitative comparison of illumina MiSeq and 454 amplicon sequencing for genotyping the highly polymorphic major histocompatibility complex (MHC) in a non-model species.BMC research notes · 2017Article
- Characterization of MHC class I in a long distance migratory wader, the Icelandic black-tailed godwit.Immunogenetics · 2017Article
- Variation in positively selected major histocompatibility complex class I loci in rufous-collared sparrows (Zonotrichia capensis).Immunogenetics · 2014Article
- Characterisation of major histocompatibility complex class I in the Australian cane toad, Rhinella marina.PloS one · 2014Article
- Comparative genome analyses reveal distinct structure in the saltwater crocodile MHC.PloS one · 2014Article
- Characteristics of MHC class I genes in house sparrows Passer domesticus as revealed by long cDNA transcripts and amplicon sequencing.Journal of molecular evolution · 2013Article
- MHC class II B diversity in blue tits: a preliminary study.Ecology and evolution · 2013Article
- In silico peptide-binding predictions of passerine MHC class I reveal similarities across distantly related species, suggesting convergence on the level of protein function.Immunogenetics · 2013Article
- Characterization of MHC class I in a long-distance migrant shorebird suggests multiple transcribed genes and intergenic recombination.Immunogenetics · 2013Article
- MHC-I affects infection intensity but not infection status with a frequent avian malaria parasite in blue tits.PloS one · 2013Article
- MHC class I of saltwater crocodiles (Crocodylus porosus): polymorphism and balancing selection.Immunogenetics · 2012Article
- Article
- Characterization and 454 pyrosequencing of major histocompatibility complex class I genes in the great tit reveal complexity in a passerine system.BMC evolutionary biology · 2012Article
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Authors and funding
6 authors.
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Abstract
The major histcompatibility complex (MHC) is a vital component of the adaptive immune system in all vertebrates. This study is the first to characterize MHC class I (MHC-I) in blue tits (Cyanistes caeruleus), and we use MHC-I exon 3 sequence data from individuals originating from three locations across Europe: Spain, the Netherlands to Sweden. Our phylogeny of the 17 blue tit MHC-I alleles contains one allele cluster with low nucleotide diversity compared to the remaining more diverse alleles. We found a significant evidence for balancing selection in the peptide-binding region in the diverse allele group only. No separation according to geographic location was found in the phylogeny of alleles. Although the number of MHC-I loci of the blue tit is comparable to that of other passerine species, the nucleotide diversity of MHC-I appears to be much lower than that of other passerine species, including the closely related great tit (Parus major) and the severely inbred Seychelles warbler (Acrocephalus sechellensis). We believe that this initial MHC-I characterization in blue tits provides an important step towards understanding the mechanisms shaping MHC-I diversity in natural populations.
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