ArticlePloS one2011
The giant Cafeteria roenbergensis virus that infects a widespread marine phagocytic protist is a new member of the fourth domain of Life.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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35 citing papers in PubMed, 66 citations in OpenAlex.
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- Quantitative Assessment of Nucleocytoplasmic Large DNA Virus and Host Interactions Predicted by Co-occurrence Analyses.mSphere · 2021Article
- Diverse Trajectories Drive the Expression of a Giant Virus in the Oomycete Plant PathogenFrontiers in microbiology · 2021Article
- The origin and evolution of viruses inferred from fold family structure.Archives of virology · 2020Review
- Virus-Host Coevolution with a Focus on Animal and Human DNA Viruses.Journal of molecular evolution · 2020Review
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- Virophages of Giant Viruses: An Update at Eleven.Viruses · 2019Review
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- Taxon Richness of "Megaviridae" Exceeds those of Bacteria and Archaea in the Ocean.Microbes and environments · 2018Article
- Multiple evolutionary origins of giant viruses.F1000Research · 2018Review
- Genome Characterization of the First Mimiviruses of Lineage C Isolated in Brazil.Frontiers in microbiology · 2017Article
- The Expanding Family of Virophages.Viruses · 2016Review
- Nothing in Evolution Makes Sense Except in the Light of Genomics: Read-Write Genome Evolution as an Active Biological Process.Biology · 2016Review
- Viral Outbreak in Corals Associated with an In Situ Bleaching Event: Atypical Herpes-Like Viruses and a New Megavirus Infecting Symbiodinium.Frontiers in microbiology · 2016Article
- Evolution of viruses and cells: do we need a fourth domain of life to explain the origin of eukaryotes?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015Article
- Review
- Evolution of double-stranded DNA viruses of eukaryotes: from bacteriophages to transposons to giant viruses.Annals of the New York Academy of Sciences · 2015Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA recent work has provided strong arguments in favor of a fourth domain of Life composed of nucleo-cytoplasmic large DNA viruses (NCLDVs). This hypothesis was supported by phylogenetic and phyletic analyses based on a common set of proteins conserved in Eukarya, Archaea, Bacteria, and viruses, and implicated in the functions of information storage and processing. Recently, the genome of a new NCLDV, Cafeteria roenbergensis virus (CroV), was released. The present work aimed to determine if CroV supports the fourth domain of Life hypothesis.
methodsA consensus phylogenetic tree of NCLDVs including CroV was generated from a concatenated alignment of four universal proteins of NCLDVs. Some features of the gene complement of CroV and its distribution along the genome were further analyzed. Phylogenetic and phyletic analyses were performed using the previously identified common set of informational genes present in Eukarya, Archaea, Bacteria, and NCLDVs, including CroV.
findingsPhylogenetic reconstructions indicated that CroV is clearly related to the Mimiviridae family. The comparison between the gene repertoires of CroV and Mimivirus showed similarities regarding the gene contents and genome organization. In addition, the phyletic clustering based on the comparison of informational gene repertoire between Eukarya, Archaea, Bacteria, and NCLDVs unambiguously classified CroV with other NCLDVs and clearly included it in a fourth domain of Life. Taken together, these data suggest that Mimiviridae, including CroV, may have inherited a common gene content probably acquired from a common Mimiviridae ancestor.
conclusionsThis further analysis of the gene repertoire of CroV consolidated the fourth domain of Life hypothesis and contributed to outline a functional pan-genome for giant viruses infecting phagocytic protistan grazers.
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