ArticleBiomedical optics express2011
Coherent anti-Stokes Raman scattering hyperspectral tissue imaging with a wavelength-swept system.
Article in Biomedical optics express, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- Nonlinear optical microscopy with an obscuration-free, freeform reflective objective.Biomedical optics express · 2025Article
- Engineering Nanomaterials for Raman Bioimaging and Theranostics: Advances, Challenges, and Future Directions.ACS omega · 2025Review
- Technological Frontiers in Brain Cancer: A Systematic Review and Meta-Analysis of Hyperspectral Imaging in Computer-Aided Diagnosis Systems.Diagnostics (Basel, Switzerland) · 2024Review
- Widely tunable fiber optical parametric oscillator synchronized with a Ti:sapphire laser for stimulated Raman scattering microscopy.Biomedical optics express · 2024Article
- Vibrational spectroscopy and multiphoton microscopy for label-free visualization of nervous system degeneration and regeneration.Biophysical reviews · 2024Review
- Wavelength-swept spontaneous Raman spectroscopy system improves fiber-based collection efficiency for whole brain tissue classification.Neurophotonics · 2024Article
- Human brain tissue identification using coherent anti-Stokes Raman scattering spectroscopy and diffuse reflectance spectroscopy for deep brain stimulation surgery.Neurophotonics · 2024Article
- Temporally optimized and spectrally shaped hyperspectral coherent anti-Stokes Raman scattering microscopy.Optics express · 2024Article
- Phase-shifting optothermal microscopy enables live-cell mid-infrared hyperspectral imaging of large cell populations at high confluency.Science advances · 2024Article
- Coherent Raman scattering microscopy: capable solution in search of a larger audience.Journal of biomedical optics · 2021Article
- Rise of Raman spectroscopy in neurosurgery: a review.Journal of biomedical optics · 2020Review
- Portable all-fiber dual-output widely tunable light source for coherent Raman imaging.Biomedical optics express · 2019Article
- Intact primate brain tissue identification using a completely fibered coherent Raman spectroscopy system.Neurophotonics · 2018Article
- Wavelength and pulse duration tunable ultrafast fiber laser mode-locked with carbon nanotubes.Scientific reports · 2018Article
- Hyperspectral imaging with laser-scanning sum-frequency generation microscopy.Biomedical optics express · 2017Article
- Nonresonant background suppression for coherent anti-Stokes Raman scattering microscopy using a multi-wavelength time-lens source.Optics express · 2016Article
- Broadband coherent Raman spectroscopy running at 24,000 spectra per second.Scientific reports · 2016Article
- 28 MHz swept source at 1.0 μm for ultrafast quantitative phase imaging.Biomedical optics express · 2015Article
- A Time-Encoded Technique for fibre-based hyperspectral broadband stimulated Raman microscopy.Nature communications · 2015Article
- Coherent Raman Scattering Microscopy in Biology and Medicine.Annual review of biomedical engineering · 2015Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We present a wavelength-swept coherent anti-Stokes Raman scattering (WS-CARS) spectroscopy system for hyperspectral imaging in thick tissue. We use a strategy where the Raman lines are excited sequentially, circumventing the need for a spectrometer. This fibre laser system, consisting of a pump laser synchronized with a rapidly tunable programmable laser (PL), can access Raman lines over a significant fraction of the high wavenumber region (2700-2950 cm(-1)) at rates of up to 10,000 spectral points per second. To demonstrate its capabilities, we have acquired WS-CARS spectra of several samples as well as images and hyperspectral images (HSI) of thick tissue both in forward and epi-detection. This instrument should be especially useful in providing local biochemical information with surrounding context supplied by imaging.
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