Evidence map›Paper›PMID 21559116›Full record

ArticleArchaea (Vancouver, B.C.)2011

More than 200 genes required for methane formation from H₂ and CO₂ and energy conservation are present in Methanothermobacter marburgensis and Methanothermobacter thermautotrophicus.

Anne-Kristin Kaster, Meike Goenrich, Henning Seedorf, Heiko Liesegang, Antje Wollherr, Gerhard Gottschalk, Rudolf K Thauer

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Archaea (Vancouver, B.C.), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 130 citations in OpenAlex.

  1. Valine overproduction inMetabolic engineering communications · 2026
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  6. Bioenergetics evolution: the link between Earth's and Life's history.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
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  16. The methanogen core and pangenome: conservation and variability across biology's growth temperature extremes.DNA research : an international journal for rapid publication of reports on genes and genomes · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. DeconstructingProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Anne-Kristin KasterMax Planck Institute for Terrestrial Microbiology, Marburg, Germany.
Meike Goenrich
Henning Seedorf
Heiko Liesegang
Antje Wollherr
Gerhard Gottschalk
Rudolf K Thauer
University of Göttingen · DEMax Planck Institute for Terrestrial Microbiology · DEMax Planck Society · DEWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The hydrogenotrophic methanogens Methanothermobacter marburgensis and Methanothermobacter thermautotrophicus can easily be mass cultured. They have therefore been used almost exclusively to study the biochemistry of methanogenesis from H₂ and CO₂, and the genomes of these two model organisms have been sequenced. The close relationship of the two organisms is reflected in their genomic architecture and coding potential. Within the 1,607 protein coding sequences (CDS) in common, we identified approximately 200 CDS required for the synthesis of the enzymes, coenzymes, and prosthetic groups involved in CO₂ reduction to methane and in coupling this process with the phosphorylation of ADP. Approximately 20 additional genes, such as those for the biosynthesis of F(430) and methanofuran and for the posttranslational modifications of the two methyl-coenzyme M reductases, remain to be identified.

Indexed as

Energy MetabolismBiosynthetic PathwaysCarbon DioxideGenes, ArchaealGenome, ArchaealHydrogenMethaneMethanobacteriaceaeOpen Reading FramesOxidation-ReductionSyntenyCarbon DioxideHydrogenMethane

Identifiers

PMID21559116
PMCPMC3087415
OpenAlexW2124148907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.