Evidence map›Paper›PMID 21558951›Full record

ArticleJournal of developmental and behavioral pediatrics : JDBP2011

Are there effects of intrauterine cocaine exposure on delinquency during early adolescence? A preliminary report.

Jessie Gerteis, Molinda Chartrand, Brett Martin, Howard J Cabral, Ruth Rose-Jacobs, Denise Crooks, Deborah A Frank

Abstract read
In one paragraph

Article in Journal of developmental and behavioral pediatrics : JDBP, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Prenatal substance exposure: What predicts behavioral resilience by early adolescence?Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2015
    Article
  4. Self-reported adolescent behavioral adjustment: effects of prenatal cocaine exposure.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2014
    Article
  5. Developmental and behavioral consequences of prenatal cocaine exposure: a review.Journal of perinatology : official journal of the California Perinatal Association · 2012
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jessie GerteisData Coordinating Center, Boston University School of Public Health, MA 02118, USA.
Molinda Chartrand
Brett Martin
Howard J Cabral
Ruth Rose-Jacobs
Denise Crooks
Deborah A Frank
Boston Medical Center · USBoston University · US

Funding

YOGA INDUCED CHANGES IN BRAIN GABA LEVELSM01RR000533 · NCRR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI ANTMAN, KAREN · 1985 to 2008
$19.4M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025771 · NCRR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI CENTER, DAVID M. · 2008 to 2011
$17.6M
Prenatal Cocaine Exposure: Young Adult Follow UpR01DA006532 · NIDA · BOSTON MEDICAL CENTER · PI FRANK, DEBORAH A, LIEBSCHUTZ, JANE M · 1990 to 2014
$12.4M
NCRR NIH HHS 1U1RR025771NCRR NIH HHS M01 RR00533.NCRR NIH HHS UL1 RR025771NIDA NIH HHS R01 DA006532NIDA NIH HHS R01DA06532
6 · The paper itself

Abstract

objectiveTo ascertain whether level of intrauterine cocaine exposure (IUCE) is associated with early adolescent delinquent behavior, after accounting for prenatal exposures to other psychoactive substances and relevant psychosocial factors.

methodsNinety-three early adolescents (12.5-14.5 years old) participating since birth in a longitudinal study of IUCE reported delinquent acts via an audio computer-assisted self-interview. Level of IUCE and exposure to cigarettes, alcohol, and marijuana were determined by maternal report, maternal and infant urine assays, and infant meconium assays at birth. Participants reported their exposure to violence on the Violence Exposure Scale for Children-Revised at ages 8.5, 9.5, and 11 years and during early adolescence, and the strictness of supervision by their caregivers during early adolescence.

resultsOf the 93 participants, 24 (26%) reported ≥ 3 delinquent behaviors during early adolescence. In the final multivariate model (including level of IUCE and cigarette exposure, childhood exposure to violence, and caregiver strictness/supervision) ≥ 3 delinquent behaviors were not significantly associated with level of IUCE but were significantly associated with intrauterine exposure to half a pack or more of cigarettes per day and higher levels of childhood exposure to violence, effects substantially unchanged after control for early adolescent violence exposure.

conclusionsIn this cohort, prospectively ascertained prenatal exposure to cigarettes and childhood exposure to violence are associated with self-reported delinquent behaviors during early adolescence. Contrary to initial popular predictions, intrauterine cocaine is not a strong predictor of adolescent delinquent behaviors in this cohort.

Indexed as

Juvenile DelinquencyAdolescentChildChi-Square DistributionCocaineCocaine-Related DisordersFemaleHumansLongitudinal StudiesMaleMultivariate AnalysisOdds RatioPregnancyPrenatal Exposure Delayed EffectsSmokingSocioeconomic FactorsCocaine

Identifiers

PMID21558951
PMCPMC3129616
OpenAlexW2043963618

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.