Evidence map›Paper›PMID 21558773›Full record

ArticleInfection control and hospital epidemiology2011

Clinical vignettes provide an understanding of antibiotic prescribing practices in neonatal intensive care units.

Sameer Patel, Timothy Landers, Elaine Larson, Theoklis Zaoutis, Patricia Delamora, David A Paul, Jennifer Wong-McLoughlin, Yu-Hui Ferng, Lisa Saiman

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Infection control and hospital epidemiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Sameer PatelDepartment of Pediatrics, Columbia University, New York, New York, USA. sp2172@columbia.edu
Timothy Landers
Elaine Larson
Theoklis Zaoutis
Patricia Delamora
David A Paul
Jennifer Wong-McLoughlin
Yu-Hui Ferng
Lisa Saiman
Columbia University · USChristiana Hospital · USCornell University · USPhiladelphia University · USThe Ohio State University · US

Funding

Improving Antimicrobial Prescribing Practices in the Neonatal Intensive Care UnitR01NR010821 · NINR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SAIMAN, LISA · 2008 to 2012
$4.6M
Training in Interdisciplinary Research to Reduce Antimicrobial Resistance (TIRAR)T90NR010824 · NINR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LARSON, ELAINE LUCILLE · 2007 to 2011
$1.0M
NINR NIH HHS R01 NR010821NINR NIH HHS R01 NR010821-02NINR NIH HHS T90 NR010824
6 · The paper itself

Abstract

objectiveTo use clinical vignettes to understand antimicrobial prescribing practices in neonatal intensive care units (NICUs).

designVignette-based survey.

settingFour tertiary care NICUs.

participantsAntibiotic prescribers in NICUs.

methodsClinicians from 4 tertiary care NICUs completed an anonymous survey containing 12 vignettes that described empiric, targeted, or prophylactic antibiotic use. Responses were compared with Centers for Disease Control and Prevention guidelines for appropriate use.

resultsOverall, 161 (59% of 271 eligible respondents) completed the survey, 37% of whom had worked in NICUs for 7 or more years. Respondents were more likely to appropriately identify use of targeted therapy for methicillin-susceptible Staphylococcus aureus, that is, use of oxacillin rather than vancomycin, than for Escherichia coli, that is, use of first-generation rather than third-generation cephalosporin, (P < .01). Increased experience significantly predicted appropriate prescribing (P = .02). The proportion of respondents choosing appropriate duration of postsurgical prophylaxis (P < .01) and treatment for necrotizing enterocolitis differed by study site (P = .03).

conclusionsThe survey provides insight into antibiotic prescribing practices and informs the development of future antibiotic stewardship interventions for NICUs.

Indexed as

HospitalistsIntensive Care, NeonatalNurse PractitionersPractice Patterns, Physicians'Anti-Bacterial AgentsData CollectionDrug Resistance, BacterialHumansAnti-Bacterial Agents

Identifiers

PMID21558773
PMCPMC3100527
OpenAlexW2032911451

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.