Evidence map›Paper›PMID 21558387›Full record

ArticleCancer research2011

National Cancer Institute Prostate Cancer Genetics Workshop.

William J Catalona, Joan E Bailey-Wilson, Nicola J Camp, Stephen J Chanock, Kathleen A Cooney, Douglas F Easton, Rosalind A Eeles, Liesel M FitzGerald, Matthew L Freedman, Julius Gudmundsson and 9 more

Open access · greenAbstract readConference Proceedings
In one paragraph

Article in Cancer research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 2 countries.

William J CatalonaDepartment of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA. wcatalona@nmff.org
Joan E Bailey-Wilson
Nicola J Camp
Stephen J Chanock
Kathleen A Cooney
Douglas F Easton
Rosalind A Eeles
Liesel M FitzGerald
Matthew L Freedman
Julius Gudmundsson
Rick A Kittles
Elliott H Margulies
Barry B McGuire
Elaine A Ostrander
Timothy R Rebbeck
Janet L Stanford
Stephen N Thibodeau
John S Witte
William B Isaacs
Cancer Genetics (United States) · USNorthwestern University · USNational Cancer Institute · USNational Human Genome Research Institute · USJohns Hopkins University · USUniversity of Illinois Chicago · US

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniela E Matei · 1993 to 2026
$153.9M
Laboratory of Translational GenomicsZIACP010201 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI PROKUNINA-OLSSON, LIUDMILA · 2010 to 2025
$91.2M
VACCINIA PSA FOR ANDROGEN-MODULATED POST-SURGICAL RECURRENCE OF PROSTATE CANCERP50CA069568 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COONEY, KATHLEEN A · 1995 to 2013
$31.3M
SUPPRESSIVE ROLE OF ANDROGEN RESPONSE GENE CALRETICULIN IN PROSTATE CANCERP50CA090386 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CRAWFORD, SUSAN · 2001 to 2013
$25.1M
MULTIDISCIPLINARY CLINICAL AND TRANSLATIONAL SCIENCE (MCTS) PROGRAM (UL1)UL1RR025741 · NCRR · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GREENLAND, PHILIP · 2008 to 2011
$24.7M
Finding Genes for Human Prostate CancerZIAHG200325 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI OSTRANDER, ELAINE · 2009 to 2021
$17.7M
Genetic Epidemiology of CancerZIAHG200331 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI BAILEY-WILSON, JOAN ELLEN · 2009 to 2022
$11.7M
Identifying and Characterizing Functional Elements in the Human GenomeZIAHG200341 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI MARGULIES, ELLIOTT · 2009 to 2011
$2.8M
Genome-wide scan for genetic variants associated with early-onset prostate cancerR01CA136621 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COONEY, KATHLEEN A · 2009 to 2012
$2.4M
Cancer Research UK 10118Cancer Research UK 11022Cancer Research UK A8385Intramural NIH HHS Z99 CA999999NCI NIH HHS P30 CA60553NCI NIH HHS P50 CA69568NCI NIH HHS P50CA90386-05S2NCI NIH HHS R01 CA136621NCI NIH HHS Y99 CA999999NCRR NIH HHS UL1 RR025741
6 · The paper itself

Abstract

Compelling evidence supports a genetic component to prostate cancer susceptibility and aggressiveness. Recent genome-wide association studies have identified more than 30 single-nucleotide polymorphisms associated with prostate cancer susceptibility. It remains unclear, however, whether such genetic variants are associated with disease aggressiveness--one of the most important questions in prostate cancer research today. To help clarify this and substantially expand research in the genetic determinants of prostate cancer aggressiveness, the first National Cancer Institute Prostate Cancer Genetics Workshop assembled researchers to develop plans for a large new research consortium and patient cohort. The workshop reviewed the prior work in this area and addressed the practical issues in planning future studies. With new DNA sequencing technology, the potential application of sequencing information to patient care is emerging. The workshop, therefore, included state-of-the-art presentations by experts on new genotyping technologies, including sequencing and associated bioinformatics issues, which are just beginning to be applied to cancer genetics.

Indexed as

Computational BiologyEthnicityGenetic Predisposition to DiseaseGenotypeHumansMaleNational Cancer Institute (U.S.)National Institutes of Health (U.S.)Polymorphism, Single NucleotideProstatic NeoplasmsSequence Analysis, DNAUnited States

Identifiers

PMID21558387
PMCPMC3096727
OpenAlexW2106844984

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.