Evidence map›Paper›PMID 21557760›Full record

ArticleBritish journal of clinical pharmacology2011

Potentially inappropriate medications in geriatric outpatients with polypharmacy: application of six sets of published explicit criteria.

Chirn-Bin Chang, Jen-Hau Chen, Chiung-Jung Wen, Hsu-Ko Kuo, I-Shu Lu, Lee-Shu Chiu, Shwu-Chong Wu, Ding-Cheng Derrick Chan

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Article in British journal of clinical pharmacology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 4 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Chirn-Bin ChangDepartment of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan.
Jen-Hau Chen
Chiung-Jung Wen
Hsu-Ko Kuo
I-Shu Lu
Lee-Shu Chiu
Shwu-Chong Wu
Ding-Cheng Derrick Chan

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimOur aim was to compare the practicability of six different potentially inappropriate medication (PIM) criteria in geriatric outpatients with polypharmacy.

methodsWe analysed baseline data from the Medication Safety Review Clinic in Taiwanese Elders (MSRC-Taiwan) study. The prevalence and correlates of PIMs were determined on the basis of criteria developed in the USA, Canada, France, Norway, Ireland and Thailand. The percentage of PIMs considered as drug-related problems and the problem-solving rate are reported.

resultsIn the 193 participants, the prevalence of PIM varied from 24 to 73%. Application of the criteria revealed that a high number of chronic medications was a common risk factor for having at least one PIM. Of the 1713 medications reviewed, 5.6-14.8% were considered PIMs. Only 30-40% of the identified PIMs were reported as drug-related problems by the MSRC team experts. Criteria with a higher number of statements and a higher percentage of local market/institution drug availability tended to detect more PIMs.

conclusionsThe prevalence of PIM varied significantly when different criteria were applied. Caution should be exercised in applying PIM criteria developed in other regions when medication availability in the local market is limited.

Indexed as

PolypharmacyAgedAged, 80 and overAge FactorsAmbulatory CareDrug UtilizationFemaleGeriatric AssessmentHumansMaleMedication ErrorsPharmaceutical PreparationsPractice Patterns, Physicians'Regression AnalysisRisk FactorsPharmaceutical Preparations

Identifiers

PMID21557760
PMCPMC3175518

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.