ReviewDevelopmental neurobiology2011
Par proteins and neuronal polarity.
Review in Developmental neurobiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Genetic Variability in Molecular Pathways Implicated in Alzheimer's Disease: A Comprehensive Review.Frontiers in aging neuroscience · 2021Pooled it
- Loss of the polarity protein Par3 promotes dendritic spine neoteny and enhances learning and memory.iScience · 2024Article
- Validating MARK2 Gene Polymorphism as a Predictor of Response to Lithium Treatment in Bipolar PatientsIranian biomedical journal · 2022Article
- In vitro reconstitution reveals phosphoinositides as cargo-release factors and activators of the ARF6 GAP ADAP1.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Case Report: A Novel Compound Heterozygous Mutation of theFrontiers in pediatrics · 2021Article
- Article
- Regulation of Polarity Protein Levels in the Developing Central Nervous System.Journal of molecular biology · 2018Review
- Phenotype-driven identification of epithelial signalling clusters.Scientific reports · 2018Article
- Crosstalk of cell polarity signaling pathways.Protoplasma · 2017Review
- Regulation of Cell Polarity by PAR-1/MARK Kinase.Current topics in developmental biology · 2017Review
- Cell Polarity in Cerebral Cortex Development-Cellular Architecture Shaped by Biochemical Networks.Frontiers in cellular neuroscience · 2017Review
- Seven in Absentia E3 Ubiquitin Ligases: Central Regulators of Neural Cell Fate and Neuronal Polarity.Frontiers in cellular neuroscience · 2017Review
- Molecular Control of Atypical Protein Kinase C: Tipping the Balance between Self-Renewal and Differentiation.Journal of molecular biology · 2016Review
- Growth and folding of the mammalian cerebral cortex: from molecules to malformations.Nature reviews. Neuroscience · 2014Review
- Atp6ap2/(pro)renin receptor interacts with Par3 as a cell polarity determinant required for laminar formation during retinal development in mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Competing molecular interactions of aPKC isoforms regulate neuronal polarity.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- ERK2-mediated phosphorylation of Par3 regulates neuronal polarization.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- New spin on an old transition: epithelial parallels in neuronal adhesion control.Trends in neurosciences · 2013Review
- aPKCλ/ι and aPKCζ contribute to podocyte differentiation and glomerular maturation.Journal of the American Society of Nephrology : JASN · 2013Article
- Regulation of microtubule stability and organization by mammalian Par3 in specifying neuronal polarity.Developmental cell · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
A hallmark of neurons is their ability to polarize with dendrite and axon specification to allow the proper flow of information through the nervous system. Over the past decade, extensive research has been performed in an attempt to understand the molecular and cellular machinery mediating this neuronal polarization process. It has become evident that many of the critical regulators involved in establishing neuronal polarity are evolutionarily conserved proteins that had previously been implicated in controlling the polarization of other cell types. At the forefront of this research are the partition defective (Par) proteins. In this review,we will provide a commentary on the progress of work regarding the central importance of Parproteins in the establishment of neuronal polarity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.