ArticleAmerican journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics2011
The familial association of tourette's disorder and ADHD: the impact of OCD symptoms.
Article in American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 52 citations in OpenAlex.
- Association Between 5-HTTLPR Polymorphism and Tics after Treatment with Methylphenidate in Korean Children with Attention-Deficit/Hyperactivity Disorder.Journal of child and adolescent psychopharmacology · 2015Trial
- Protocol for developing an evidence-based expert consensus on efficacy evaluation and comorbidity management of integrated Chinese and Western medicine for pediatric tic disorders: a GRADE-based modified Delphi study.Frontiers in neurology · 2026Article
- The Association of Quality of Life with Psychosocial Factors in Adolescents with Tourette Syndrome.Child psychiatry and human development · 2025Article
- Neuropsychiatric symptoms in siblings of children with Tourette syndrome in the EMTICS study.JCPP advances · 2025Article
- Co-Occurrence of Tic Disorders and Attention-Deficit/Hyperactivity Disorder-Does It Reflect a Common Neurobiological Background?Biomedicines · 2022Review
- Tourette's Syndrome, OCD and ADHD as a Triad in Neurofibromatosis Type 1: A Case Report.Indian journal of psychological medicine · 2022Article
- Whole-exome sequencing identifies genes associated with Tourette's disorder in multiplex families.Molecular psychiatry · 2021Article
- Empiric Recurrence Risk Estimates for Chronic Tic Disorders: Implications for Genetic Counseling.Frontiers in neurology · 2020Article
- Prenatal Maternal Smoking and Tourette Syndrome: A Nationwide Register Study.Child psychiatry and human development · 2016Article
- The Fallacy of Univariate Solutions to Complex Systems Problems.Frontiers in neuroscience · 2016Article
- Familiality of Co-existing ADHD and Tic Disorders: Evidence from a Large Sibling Study.Frontiers in psychology · 2016Article
- NMDA receptor agonists reverse impaired psychomotor and cognitive functions associated with hippocampal Hbegf-deficiency in mice.Molecular brain · 2015Article
- Web-based phenotyping for Tourette Syndrome: Reliability of common co-morbid diagnoses.Psychiatry research · 2015Article
- Multidisciplinary clinic dedicated to treating youth with pediatric acute-onset neuropsychiatric syndrome: presenting characteristics of the first 47 consecutive patients.Journal of child and adolescent psychopharmacology · 2015Article
- Association of ADORA1 rs2228079 and ADORA2A rs5751876 Polymorphisms with Gilles de la Tourette Syndrome in the Polish Population.PloS one · 2015Article
- Association study of dopamine transporter gene (DAT1) variable tandem repeat sequence (VNTR) with obsessive-compulsive disorder in Chinese Han Population.International journal of clinical and experimental medicine · 2015Article
- The Inheritance of Tourette Disorder: A review.Journal of obsessive-compulsive and related disorders · 2014Article
- Association of the KCNJ5 gene with Tourette Syndrome and Attention-Deficit/Hyperactivity Disorder.Genes, brain, and behavior · 2014Article
- Genetic susceptibility and neurotransmitters in Tourette syndrome.International review of neurobiology · 2013Review
- Tourette syndrome in youth with and without obsessive compulsive disorder and attention deficit hyperactivity disorder.European child & adolescent psychiatry · 2012Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
Abstract
Tourette's disorder (TD) frequently co-occurs with attention-deficit/hyperactivity disorder (ADHD) and obsessive compulsive disorder (OCD). While the relationship between TD and OCD suggests that they share etiological factors, the exact relationship between TD and ADHD is less clear. The goal of the current analyses was to understand better the familial relationship between DSM-IV ADHD and TD. Direct interview diagnostic data from a case-control study of 692 relatives of 75 comorbid TD and ADHD (TD + ADHD), 74 TD without ADHD (TD Only), 41 ADHD without TD (ADHD Only), and 49 control probands were analyzed. Hierarchical loglinear modeling was used to explore association patterns between TD, ADHD, and OCD or sub-clinical OCD (OCD/OCDsub) diagnoses among the 190 affected probands and their 538 relatives. The presence of OCD or OCDsub diagnosis in a proband was associated with a significantly increased risk of comorbid TD + ADHD in his/her relatives. The finding of an association between TD, ADHD and a proband OCD/OCDsub diagnosis was unexpected. The current results suggest that TD, ADHD, and OCD symptoms have overlapping neurobiology when occurring in families of TD and/or ADHD probands.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.