Evidence map›Paper›PMID 21556881›Full record

ReviewCurrent allergy and asthma reports2011

Immunologic similarities between selected autoimmune diseases and peanut allergy: possible new therapeutic approaches.

Michael A Martucci, Stephen C Dreskin

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current allergy and asthma reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael A MartucciDepartment of Medicine, University of Colorado Denver School of Medicine, Campus Box B164, 12700 East 19th Avenue, Room 10002, Aurora, CO 80045, USA.
Stephen C Dreskin

Funding

Redefining the Major Peanut AllergensR01AI052164 · NIAID · UNIVERSITY OF COLORADO DENVER · PI DRESKIN, STEPHEN C · 2003 to 2011
$3.0M
NIAID NIH HHS R01-AI052164
6 · The paper itself

Abstract

Food allergies are an important medical problem in Westernized countries. Allergy to peanuts is a dramatic example of a food allergy that tends to be particularly severe and long-lived. This article examines food allergy-specifically peanut allergy-from the perspective that tolerance to foods is a normal state, just as tolerance to self-proteins is a normal state. From this vantage point, loss of tolerance to foods in food-allergic individuals can be viewed as parallel to the loss of tolerance to self-proteins in those with autoimmune diseases. Although our knowledge base is far from satisfactory, there are important similarities in the immunologic abnormalities that are characteristic of both peanut allergy and several autoimmune diseases. Delineation of these similarities may open the door to new therapeutic approaches for the treatment of severe food allergies.

Indexed as

Immune ToleranceAutoimmune DiseasesHumansPeanut Hypersensitivity

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.