ArticleEuropean journal of applied physiology2012
Influence of moderate hypoxia on tolerance to high-intensity exercise.
Article in European journal of applied physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Alterations in acid-base balance and high-intensity exercise performance after short-term and long-term exposure to acute normobaric hypoxic conditions.Scientific reports · 2020Trial
- Trial
- Determinants of curvature constant (W') of the power duration relationship under normoxia and hypoxia: the effect of pre-exercise alkalosis.European journal of applied physiology · 2017Trial
- Trial
- Quadriceps Muscle Length Differentially Affects Exercise Capacity, the Torque-Duration Relationship, and Neuromuscular Fatigue.Scandinavian journal of medicine & science in sports · 2026Article
- Effect of hypoxia on muscle activation at equivalent absolute and relative intensity during incremental and constant load exercise to task failure.Experimental physiology · 2026Article
- Skeletal muscle mitochondrial correlates of critical power and W' in healthy active individuals.Experimental physiology · 2025Article
- Utility of the Respiratory Compensation Point for Estimating Critical Power: Insights From Normoxia and Hypoxia.European journal of sport science · 2025Article
- Interaction of Factors Determining Critical Power.Sports medicine (Auckland, N.Z.) · 2023Review
- Influence and Mechanisms of Action of Environmental Stimuli on Work Near and Above the Severe Domain Boundary (Critical Power).Sports medicine - open · 2022Review
- The impact of elevated body core temperature on critical power as determined by a 3-min all-out test.Journal of applied physiology (Bethesda, Md. : 1985) · 2021Article
- Influence of muscular contraction on vascular conductance during exercise above versus below critical power.Respiratory physiology & neurobiology · 2021Article
- Physiological Evidence That the Critical Torque Is a Phase Transition, Not a Threshold.Medicine and science in sports and exercise · 2020Article
- The maximal metabolic steady state: redefining the 'gold standard'.Physiological reports · 2019Review
- Influence of group III/IV muscle afferents on small muscle mass exercise performance: a bioenergetics perspective.The Journal of physiology · 2018Article
- Limitation of Maximal Heart Rate in Hypoxia: Mechanisms and Clinical Importance.Frontiers in physiology · 2018Review
- The effects of exercise-induced muscle damage on critical torque.European journal of applied physiology · 2017Article
- Skeletal muscle bioenergetics during all-out exercise: mechanistic insight into the oxygen uptake slow component and neuromuscular fatigue.Journal of applied physiology (Bethesda, Md. : 1985) · 2017Article
- Prediction of Critical Power and W' in Hypoxia: Application to Work-Balance Modelling.Frontiers in physiology · 2017Article
- Critical Power: An Important Fatigue Threshold in Exercise Physiology.Medicine and science in sports and exercise · 2016Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It remains uncertain as how the reduction in systemic oxygen transport limits high-intensity exercise tolerance. 11 participants (5 males; age 35 ± 10 years; peak [Formula: see text] 3.5 ± 0.4 L min(-1)) performed cycle ergometry to the limit of tolerance: (1) a ramp test to determine ventilatory threshold (VT) and peak [Formula: see text]; (2) three to four constant-load tests in order to model the linear P-t (-1) relationship for estimation of intercept (critical power; CP) and slope (AWC). All tests were performed in a random order under moderate hypoxia (FiO(2) = 0.15) and normoxia. The linearity of the P-t (-1) relationship was retained under hypoxia, with a systematic reduction in CP (220 ± 25 W vs. 190 ± 28 W; P < 0.01) but no significant difference in AWC (11.7 ± 5.5 kJ vs. 12.1 ± 4.4 kJ; P > 0.05). However, large individual variations in the change of the latter were observed (-36 to +66%). A significant relationship was found between the % change in CP (r = 0.80, P < 0.01) and both peak [Formula: see text] (CP: r = -0.65, P < 0.05) and VT values recorded under normoxia (CP: r = -0.65, P < 0.05). The present study demonstrates the aerobic nature of the intercept of the P-t (-1) relationship, i.e. CP. However, the extreme within-individual changes in AWC do not support the original assumption that AWC reflects a finite energy store. Lower hypoxia-induced decrements in CP were observed in aerobically fitter participants. This study also demonstrates the greater ability these participants have to exercise at supra-CP but close to CP workloads under moderate hypoxia.
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Registered trials
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