ArticleInternational journal of general medicine2011
Importance of innate mucosal immunity and the promises it holds.
Article in International journal of general medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- A scalable human gut-immune co-culture model for evaluating inflammatory bowel disease anti-inflammatory therapies.SLAS discovery : advancing life sciences R & D · 2025Article
- Effect of Marine-Derived Scallop Peptide Hydrolysate on Immune Modulation and Gut Microbiota Restoration in Cyclophosphamide-Induced Immunosuppressed Mice.Food science & nutrition · 2025Article
- Agricultural Employer Perspectives on Occupational Wildfire Smoke Rules.Journal of agromedicine · 2025Article
- Nanoparticle-Driven Modulation of Mucosal Immunity and Interplay with the Microbiome.Journal of microbiology and biotechnology · 2025Review
- Article
- Recent Advances in Oral Vaccines for Animals.Veterinary sciences · 2024Review
- Characterization ofFrontiers in cellular and infection microbiology · 2024Article
- Effects of Shrimp Peptide Hydrolysate on Intestinal Microbiota Restoration and Immune Modulation in Cyclophosphamide-Treated Mice.Molecules (Basel, Switzerland) · 2022Article
- Nasal vaccination against SARS-CoV-2: Synergistic or alternative to intramuscular vaccines?International journal of pharmaceutics · 2021Review
- The ocular surface immune system through the eyes of aging.The ocular surface · 2021Review
- Intra-nasal zinc level relationship to COVID-19 anosmia and type 1 interferon response: A proposal.Laryngoscope investigative otolaryngology · 2021Article
- Gene expression based evidence of innate immune response activation in the epithelium with oral lichen planus.Archives of oral biology · 2014Article
- Development of mucosal immunity in children: a rationale for sublingual immunotherapy?Journal of allergy · 2012Article
- Anatomical site-specific contributions of pneumococcal virulence determinants.Pneumonia (Nathan Qld.)Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The body defense mechanism has evolved to protect animals from invading pathogenic microorganisms and cancer. It is able to generate a diverse variety of cells and molecules capable of specifically recognizing and eliminating a limitless variety of foreign invaders. These cells and molecules act together in a dynamic network and are known as the immune system. Innate mucosal immunity consists of various recognition receptor molecules, including toll-like receptors, NOD-like receptors, and RIG-I-like receptors. These recognition receptor molecules recognize various invading pathogens effectively, and generate an immune response to stop their entry and neutralize their adverse consequences, such as tissue damage. Furthermore, they regulate the adaptive response in cases of severe infection and also help generate a memory response. Most infections occur through the mucosa. It is important to understand the initial host defense response or innate immunity at the mucosal surface to control these infections and protect the system. The aim of this review is to discuss the effects and functions of various innate mucosal agents and their importance in understanding the physiological immune response, as well as their roles in developing new interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.