ArticleHealth affairs (Project Hope)2011
Discovering how environmental exposures alter genes could lead to new treatments for chronic illnesses.
Article in Health affairs (Project Hope), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence of Common Gynecological Conditions in the Middle East: Systematic Review and Meta-Analysis.Frontiers in reproductive health · 2021Pooled it
- The Navigation Guide systematic review methodology: a rigorous and transparent method for translating environmental health science into better health outcomes.Environmental health perspectives · 2014Pooled it
- First report of tinea corporis caused by Trichophyton quinckeanum in Iran and its antifungal susceptibility profile.Current medical mycology · 2022Article
- Epigenetic Mechanisms in the Neurodevelopmental Theory of Depression.Depression research and treatment · 2020Review
- The utility of a system dynamics approach for understanding cumulative health risk from exposure to environmental hazards.Environmental research · 2019Article
- Hybrid Resiliency-Stressor Conceptual Framework for Informing Decision Support Tools and Addressing Environmental Injustice and Health Inequities.International journal of environmental research and public health · 2019Article
- The Socio-Exposome: Advancing Exposure Science and Environmental Justice in a Post-Genomic Era.Environmental sociology · 2017Article
- Article
- Enacting the molecular imperative: How gene-environment interaction research links bodies and environments in the post-genomic age.Social science & medicine (1982) · 2016Article
- Association of TP53 PIN3 polymorphism with breast cancer in Moroccan population.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014Article
- A biobehavioral perspective on telomere length and the exposome.Biological research for nursing · 2014Article
- Risk communication and decision tools for children's health protection.Birth defects research. Part C, Embryo today : reviews · 2013Review
- Toxic environmental chemicals: the role of reproductive health professionals in preventing harmful exposures.American journal of obstetrics and gynecology · 2012Article
- Looking to the future: incorporating genomic information into disparities research to reduce measurement error and selection bias.Health services research · 2012Article
- Ethical concerns related to developing pharmacogenomic treatment strategies for addiction.Addiction science & clinical practice · 2011Article
- An Epigenetic Perspective on Lifestyle Medicine for Depression: Implications for Primary Care Practice.American journal of lifestyle medicineReview
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Emerging research demonstrates that diet, pollution, and other environmental triggers can alter both the function and expression of human genes and lead to a heightened disease risk. These environment-gene interactions can cause so-called epigenetic changes in gene expression-patterns of which genes are switched "on" or "off"-that may account for the rising mortality from chronic diseases in industrialized nations. In this paper, we call for a new transdisciplinary approach to public health that would examine how environmental exposures, both physical and social, influence gene expression and a person's susceptibility to chronic disease. This initiative could lead to new ways to prevent and treat such illnesses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.