ArticleArthritis research & therapy2011
Antinuclear antibodies in healthy people: the tip of autoimmunity's iceberg?
Article in Arthritis research & therapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 47 citations in OpenAlex.
- Association of serum complement C3 level with disease severity in primary pterygium.Frontiers in medicine · 2025Article
- The Adaptation Model of Immunity: Signal IV Matters Most in Determining the Functional Outcomes of Immune Responses.Journal of immunology (Baltimore, Md. : 1950) · 2023Article
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- Association between Changes in the Patterns of Antinuclear Autoantibodies during Immune Checkpoint Inhibition Therapy and the Development of Severe Immune Related Adverse Events.International journal of molecular sciences · 2022Article
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- Autoimmunity in Human CE: Correlative with The Fertility Status of The CE Cyst.Helminthologia · 2022Article
- DNA Microsystems for Biodiagnosis.Micromachines · 2020Review
- Study of Anti-Malarials in Incomplete Lupus Erythematosus (SMILE): study protocol for a randomized controlled trial.Trials · 2018Article
- Detection of autoimmune antibodies in localized scleroderma by synthetic oligonucleotide antigens.PloS one · 2018Article
- The Diagnosis and Treatment of Sjögren's Syndrome.Deutsches Arzteblatt international · 2017Review
- Lack of Clinical Relevance of ANA and ASMA Positivity in Patients with Liver Transplantation without a History of Autoimmune Diseases.BioMed research international · 2017Article
- Autoantibodies in breast cancer sera are not epiphenomena and may participate in carcinogenesis.BMC cancer · 2015Article
- The prevalence of autoantibodies in complex regional pain syndrome type I.Mediators of inflammation · 2015Article
- The complex role of DNA, histones and HMGB1 in the pathogenesis of SLE.Autoimmunity · 2014Review
- High prevalence of antinuclear antibodies in children with thyroid autoimmunity.Journal of immunology research · 2014Article
- Determination of anti-nuclear antibody seroprevalence in adult age groups in trabzon province.Balkan medical journal · 2013Article
- Targeting the B-cell pathway in lupus nephritis: current evidence and future perspectives.TheScientificWorldJournal · 2013Review
- Autoantibody profiling to follow evolution of lupus syndromes.Arthritis research & therapy · 2012Article
- Serologic laboratory findings in malignancy.Rheumatic diseases clinics of North America · 2011Review
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Abstract
Antinuclear antibodies (ANAs) are venerable biomarkers for assessing the diagnosis and prognosis of patients with autoimmunity. While closely associated with diseases such as systemic lupus erythematosus, ANA expression occurs commonly in healthy people. The basis for this expression is unknown, although it may reflect features of the assays for antibody detection or intrinsic immunological disturbances in otherwise normal individuals. Like autoimmunity itself, ANA expression is more common among women than men, pointing to an important determinant of these responses. Future research will clarify the mechanisms of ANA expression and the utility of current assays as antecedent and screening biomarkers.
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