ArticleHealth services research2011
Adverse drug events in U.S. adult ambulatory medical care.
Article in Health services research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 5 syntheses or guidelines pooled it, 127 citations in OpenAlex.
- Predicting adverse drug event using machine learning based on electronic health records: a systematic review and meta-analysis.Frontiers in pharmacology · 2024Pooled it
- Pooled it
- Racial and Ethnic Disparities in Adverse Drug Events: A Systematic Review of the Literature.Journal of racial and ethnic health disparities · 2015Pooled it
- Health outcomes associated with polypharmacy in community-dwelling older adults: a systematic review.Journal of the American Geriatrics Society · 2014Pooled it
- Ambulatory Medication Safety in Primary Care: A Systematic Review.Journal of the American Board of Family Medicine : JABFMPooled it
- The electronic medication complete communication (EMCContemporary clinical trials · 2016Trial
- Assessing Associations of Three Types of Higher-Risk Medication Use and Mortality in Older Adults.Journal of the American Geriatrics Society · 2026Article
- Slipping Through the Chasm of Multicenter Hand-offs-Rare Incidence of Nintedanib Induced Renal Failure: Case Report.Journal of community hospital internal medicine perspectives · 2026Article
- Enhancing medication safety engagement among older adults with diabetes and comorbidities: a quasi-experimental study protocol.BMJ open · 2025Article
- The Prevalence of Potential Opportunities for Simultaneous Medication Prescribing and Deprescribing in Older Adults.Journal of general internal medicine · 2025Article
- Real-world FAERS safety analysis of Pralsetinib.Scientific reports · 2025Article
- Enhancing the Role of Community Pharmacists in Medication Safety: A Qualitative Study of Voices from the Frontline.Pharmacy (Basel, Switzerland) · 2025Article
- Adverse Drug Events in Ambulatory Care: A Cross-Sectional Study.Drug safety · 2025Article
- Postdischarge Care of Acute Kidney Injury Survivors: An Opportunity for Targeted Nurse and Pharmacist Interventions.Advances in kidney disease and health · 2025Review
- Ambulatory Medication Change Workflows' Effect on Communication to Pharmacies.Applied clinical informatics · 2025Article
- What should patients learn? Co-designing patient education to improve medication safety, professional-patient communication, and partnership.Frontiers in medicine · 2025Article
- Assessing patient work system factors for medication management during transition of care among older adults: an observational study.BMJ quality & safety · 2024Observational
- Phenotyping Adherence Through Technology-Enabled Reports and Navigation (the PATTERN Study): Qualitative Study for Intervention Adaptation Using the Exploration, Preparation, Implementation, and Sustainment Framework.JMIR formative research · 2024Article
- How Safe are Outpatient Electronic Health Records? An Evaluation of Medication-Related Decision Support using the Ambulatory Electronic Health Record Evaluation Tool.Applied clinical informatics · 2023Article
- An Early Adverse Drug Event Detection Approach with False Discovery Rate Control.medRxiv : the preprint server for health sciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo estimate the incidence of adverse drug events (ADEs) associated with health care visits among U.S. adults across all ambulatory settings. DATA SOURCE: We analyzed data from two nationally representative probability sample surveys: the National Ambulatory Medical Care Survey and the National Hospital and Ambulatory Medical Care Survey. From 2005 to 2007, the presence of an ADE was specifically defined, requested, and recorded in these surveys. STUDY
designSecondary data analysis. PRINCIPAL
findingsAn estimated 13.5 million ADE-related visits occurred between 2005 and 2007 (0.5 percent of all visits), the large majority (72 percent) occurring in outpatient practice settings, and the remaining in emergency departments. Older patients (age ≥65 years) had the highest age-specific ADE rate, 3.8 ADEs per 10,000 persons per year. In adjusted analyses of outpatient visits, there was an increased odds of an ADE-related visit with increased medication burden (odds ratio [OR] for six to eight medications compared with no medications, OR 3.83 [2.20, 6.65]), and increased odds of ADEs associated with primary care visits compared with specialty visits (OR 2.22 [1.70, 2.89]).
conclusionsApproximately 4.5 million ambulatory visits related to ADEs occur each year, the majority of these in outpatient office practices. A greater focus on ADE prevention and detection is warranted among patients receiving multiple medications in primary care practices.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.