Evidence map›Paper›PMID 21553130›Full record

ArticleImmunogenetics2011

ULBP4/RAET1E is highly polymorphic in the Old World monkey.

Taeko K Naruse, Yukiko Okuda, Kazuyasu Mori, Hirofumi Akari, Tetsuro Matano, Akinori Kimura

Abstract read
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In one paragraph

Article in Immunogenetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Diversity of ULBP5 in Old-World monkeys (Cercopithecidae) and divergence of the ULBP gene family in primates.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Taeko K NaruseDepartment of Molecular Pathogenesis, Medical Research Institute, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Japan.
Yukiko Okuda
Kazuyasu Mori
Hirofumi Akari
Tetsuro Matano
Akinori Kimura
Tokyo Medical and Dental University · JPKyoto University of Education · JPNational Institute of Infectious Diseases · JPThe University of Tokyo · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural-killer group 2 member D (NKG2D) is an activating receptor that plays an important role in the immune response mediated by NK cells, γδ(+) T cells, and CD8(+) T cells. In humans, MHC class I chain-related genes and UL-16 binding protein (ULBP)/retinoic acid early transcript 1 (REAT1) gene family encode ligands for NKG2D. The rhesus and crab-eating macaques, which belong to the Old World monkeys, are widely used as non-human primate models in medical researches on the immunological process. In the present study, we investigated the polymorphisms of ULBP4/RAET1E, a member of the ULBP/RAET1 family, and found 25 and 14 alleles from the rhesus and crab-eating macaques, respectively, of which diversities were far more extended than in humans. A phylogenetic study suggested that the allelic diversification of ULBP4/RAET1E predated the divergence of rhesus and crab-eating macaques.

Indexed as

Polymorphism, GeneticAmino Acid SequenceAnimalsCarrier ProteinsHistocompatibility Antigens Class IHumansMacaca fascicularisMacaca mulattaMembrane ProteinsMolecular Sequence DataPhylogenySequence AlignmentCarrier ProteinsHistocompatibility Antigens Class IMembrane Proteins

Identifiers

PMID21553130
OpenAlexW1972281551

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.