ArticleCancer causes & control : CCC2011
Association between psoriasis and incident cancer: the Iowa's Women's Health Study.
Article in Cancer causes & control : CCC, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Association between psoriasis and lung cancer: two-sample Mendelian randomization analyses.BMC pulmonary medicine · 2023Pooled it
- Prevalence, Incidence, and Risk of Cancer in Patients With Psoriasis and Psoriatic Arthritis: A Systematic Review and Meta-analysis.JAMA dermatology · 2020Pooled it
- Association of Psoriasis With the Risk of Developing or Dying of Cancer: A Systematic Review and Meta-analysis.JAMA dermatology · 2019Pooled it
- Association between physical activity and risk of prevalent psoriasis: A MOOSE-compliant meta-analysis.Medicine · 2018Pooled it
- Insufficient or excessive exercise activities are associated with suboptimal treatment outcomes in patients with psoriasis: a longitudinal study in shanghai, China.Annals of medicine · 2026Article
- The Intersection of Psoriasis and Neoplasia: Risk Factors, Therapeutic Approaches, and Management Strategies.Cancers · 2024Review
- Identification of Hub Genes for Psoriasis and Cancer by Bioinformatic Analysis.BioMed research international · 2024Article
- Deciphering the causal association and co-disease mechanisms between psoriasis and breast cancer.Frontiers in immunology · 2024Article
- The causal relationship between psoriasis and cancers: a two-sample Mendelian randomization analysis.Frontiers in oncology · 2024Article
- Mechanism of Huoluo Xiaoling Dan in the Treatment of Psoriasis Based on Network Pharmacology and Molecular Docking.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Psoriasis and Exercise: A Review.Psoriasis (Auckland, N.Z.) · 2022Review
- Cardiorespiratory fitness in late adolescence and long-term risk of psoriasis and psoriatic arthritis among Swedish men.PloS one · 2021Article
- Digestive system in psoriasis: an update.Archives of dermatological research · 2017Review
- The Risk of Cancer in Patients With Psoriasis: A Population-Based Cohort Study in the Health Improvement Network.JAMA dermatology · 2016Article
- Risk factors for pancreatitis in older women: the Iowa Women's Health Study.Annals of epidemiology · 2015Article
- Cancer risk in immune-mediated inflammatory diseases (IMID).Molecular cancer · 2013Review
- The association between physical activity and the risk of incident psoriasis.Archives of dermatology · 2012Article
- Multiple associations between a broad spectrum of autoimmune diseases, chronic inflammatory diseases and cancer.Anticancer research · 2012Review
- Psoriasis is associated with a greater risk of incident venous thromboembolism: the Iowa Women's Health Study.Journal of thrombosis and haemostasis : JTH · 2012Article
- The Relationship of Psoriasis and Melanocytic Nevi.Indian journal of dermatologyArticle
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
introductionStudies have reported higher cancer risk in individuals with psoriasis, a chronic inflammatory autoimmune disease; however, adjustment for potential confounders was lacking.
methodsWe examined the association of psoriasis with cancer incidence in 32,910 women after age 65 in the IWHS cohort linked to Medicare. Psoriasis was defined as: 2+ psoriasis claims from any Medicare file during 1991-2004 or 1+ psoriasis claim from a dermatologist (n = 719). Severe psoriasis was defined as 4+ psoriasis claims from a dermatologist in any year (n = 121). Cox proportional hazards regression, with psoriasis as a time-dependent variable was conducted to calculate hazard ratios (HR) and 95% confidence intervals (CI) of total (n = 6,488), breast (n = 2,066), lung (n = 742), and colon cancers (n = 947).
resultsWith age-adjustment, psoriasis (yes vs. no) was associated with increased risk of lung 1.9 (95% CI: 1.2-3.0), colon 1.6 (95% CI: 1.1-2.5), and total cancer 1.2 (95% CI, 1.0-1.4). After further adjustment for smoking, body mass index, education, physical activity, and hormone therapy use, only the association for colon cancer remained statistically significant (HR = 1.6, 95% CI: 1.0-2.4) and was stronger for severe psoriasis.
conclusionThe observed association between psoriasis and colon cancer may reflect inflammatory or unidentified processes.
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