ArticleEuropean journal of clinical pharmacology2011
Antidepressants utilization among elderly in Lombardy from 2000 to 2007: dispensing trends and appropriateness.
Article in European journal of clinical pharmacology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Antidepressant use in the Canary Islands (Spain): a retrospective study of provincial, island and municipal trends and associated factors.Frontiers in pharmacology · 2025Article
- Trends in the Consumption of Antidepressant Drugs before and during the COVID-19 Pandemic in the Canary Islands, Spain: The Case of the Province of Las Palmas.Healthcare (Basel, Switzerland) · 2023Article
- [Effects of COVID-19 on the consumption of antidepressants in the Province of Santa Cruz de Tenerife, Canary Islands].Farmaceuticos comunitarios · 2023Article
- Prescription Appropriateness of Drugs for Peptic Ulcer and Gastro-Esophageal Reflux Disease: Baseline Assessment in the LAPTOP-PPI Cluster Randomized Trial.Frontiers in pharmacology · 2022Article
- Frequency and predictors of the potential overprescribing of antidepressants in elderly residents of a geographically defined U.S. population.Pharmacology research & perspectives · 2019Article
- Changes in prevalence of psychotropic drug use and alcohol consumption among the elderly in Germany: results of two National Health Interview and Examination Surveys 1997-99 and 2008-11.BMC psychiatry · 2017Article
- Patterns of antidepressant use in Italy: therapy duration, adherence and switching.Clinical drug investigation · 2015Article
- Concurrent Use of Benzodiazepines and Antidepressants and the Risk of Motor Vehicle Accident in Older Drivers: A Nested Case-Control Study.Neurology and therapy · 2015Article
- Trends in the dispensation of antidepressant drugs over the past decade (2000-2010) in Andalusia, Spain.Social psychiatry and psychiatric epidemiology · 2015Article
- Prescription and indication trends of antidepressant drugs in the Netherlands between 1996 and 2012: a dynamic population-based study.European journal of clinical pharmacology · 2015Article
- Antidepressant use and lifetime history of mental disorders in a community sample: results from the Baltimore Epidemiologic Catchment Area Study.The Journal of clinical psychiatry · 2015Article
- Time trends of antidepressant drug prescriptions in men versus women in a geographically defined US population.Archives of women's mental health · 2014Article
- Changes in prescribing patterns and clinical outcomes in elderly diabetic patients in 2000 and 2010: analysis of a large Italian population-based study.European journal of clinical pharmacology · 2014Article
- Antidepressant prescribing in five European countries: application of common definitions to assess the prevalence, clinical observations, and methodological implications.European journal of clinical pharmacology · 2014Article
- Changes in drug prescribing to Italian community-dwelling elderly people: the EPIFARM-Elderly Project 2000-2010.European journal of clinical pharmacology · 2014Article
- Changes in the prescribing pattern of antidepressant drugs in elderly patients: an Italian, nationwide, population-based study.European journal of clinical pharmacology · 2014Article
- Trend in SSRI-SNRI antidepressants prescription over a 6-year period and predictors of poor adherence.European journal of clinical pharmacology · 2013Article
- New prescriptions of spironolactone associated with angiotensin-converting-enzyme inhibitors and/or angiotensin receptor blockers and their laboratory monitoring from 2001 to 2008: a population study on older people living in the community in Italy.European journal of clinical pharmacology · 2013Article
- Dopaminergic and serotonergic drug use: a nationwide register-based study of over 1,300,000 older people.PloS one · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate the prevalence and incidence of antidepressant (AD) use in the elderly during an 8-year period and to evaluate AD treatment appropriateness.
methodsA population-based dispensation study on community-dwelling elderly of a large area in Lombardy was performed. Data were drawn from the regional administrative database and from a general practice registry. For each year, prevalence of AD use (i.e., at least one recorded dispensation) and AD treatment (i.e., at least four recorded dispensations) was compared.
resultsThe prevalence of AD use and treatment doubled and tripled, respectively. The greatest shift occurred between 2000 and 2002 and was entirely due to SSRIs. The most pronounced increase was seen in females who accounted for 72% of all dispensations. The increase in prevalence was not mirrored by incident use, which slightly decreased (OR: 0.98; 95% CI: 0.98-0.98). The proportion of those who received a minimally adequate AD treatment grew over the years (OR: 1.63; 95% CI: 1.59-1.68). The increase in prevalence of AD treatment was most pronounced among older age groups (ORs between 1.02 and 1.06 for age classes ≥75 years relative to the 65-69 age class; P < 0.001) and was proportional to that of depressive disorders.
conclusionsA dramatic rise in dispensations was observed. The increasing prevalence of minimally adequately treated subjects and a possible decrease in untreated depression may reflect an improvement in the pharmacological treatment of depression. The increase in prevalence and not in the incidence of dispensations could be related to an inappropriate prolongation of treatment duration.
Indexed as
Identifiers
21553002What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.