Evidence map›Paper›PMID 21552721›Full record

ArticleJournal of applied oral science : revista FOB2011

Pleomorphic adenoma with extensive squamous metaplasia and keratin cyst formations in minor salivary gland: a case report.

Maria Carolina Vaz Goulart, Patrícia Freitas-Faria, Gláuter Rodrigues Goulart, Adriano Macedo de Oliveira, Roman Carlos-Bregni, Cleverson Teixeira Soares, Vanessa Soares Lara

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Journal of applied oral science : revista FOB, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Article
  3. An Unusual Presentation of Keratinous Cyst - A Case Report.Journal of orthopaedic case reports · 2025
    Article
  4. Review
  5. Pleomorphic Adenoma with Extensive Squamous and Adipocytic Metaplasia Mimicking as Low Grade Mucoepidermoid Carcinoma on FNAC.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2022
    Article
  6. Article
  7. Article
  8. Squamous Metaplasia in Pleomorphic Adenoma: A Diagnostic and Prognostic Enigma.Journal of pathology and translational medicine · 2018
    Article
  9. Keratinizing pleomorphic adenoma: An unusual case report.Journal of oral and maxillofacial pathology : JOMFP · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Maria Carolina Vaz GoulartDepartment of Stomatology (Oral Pathology), Bauru School of Dentistry, University of São Paulo, Bauru, SP, Brazil. mariacarolinaodonto@yahoo.com.br
Patrícia Freitas-Faria
Gláuter Rodrigues Goulart
Adriano Macedo de Oliveira
Roman Carlos-Bregni
Cleverson Teixeira Soares
Vanessa Soares Lara
Centro Universitario de Occidente · GTInstituto Lauro de Souza Lima · BRUniversidade José do Rosário Vellano · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pleomorphic adenoma (PA), the most common salivary gland tumor, accounts for 54 to 65% of all salivary gland neoplasias and 80% of the benign salivary gland tumors. It most frequently affects the parotid gland, followed by the submandibular and the minor salivary glands. Microscopically, mucous, sebaceous, oncocytic and squamous metaplasia, sometimes with the formation of keratin pearls, may be present, but the latter rarely results in the formation of extensive keratin-filled cysts lined by squamous epithelium. Extensive squamous metaplasia can be mistaken for malignancy, including mucoepidermoid carcinoma and squamous cell carcinoma. Here, we present an unusual case of PA with extensive squamous metaplasia and keratin cyst formations in a minor salivary gland, and discuss its microscopic features, including the immunohistochemical characteristics, and differential diagnosis of this uncommon presentation.

Indexed as

Adenoma, PleomorphicAdultHumansImmunohistochemistryKeratinsMaleMetaplasiaSalivary Gland NeoplasmsSalivary Glands, MinorKeratins

Identifiers

PMID21552721
PMCPMC4243758
OpenAlexW2165979115

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.