Evidence map›Paper›PMID 21551386›Full record

ReviewAmerican journal of public health2011

Cumulative risk assessment for combined health effects from chemical and nonchemical stressors.

Ken Sexton, Stephen H Linder

Open access · greenAbstract readReview
In one paragraph

Review in American journal of public health, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
28.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 101 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. FIGO committee opinion: Environmental drivers of obstetric health and early childhood development.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Article
  6. FIGO committee opinion: Environmental drivers of gynecologic and reproductive health.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Article
  7. Article
  8. Article
  9. Addressing systemic problems with exposure assessments to protect the public's health.Environmental health : a global access science source · 2023
    Review
  10. Article
  11. Article
  12. Accounting for Health Risk Inequality in Regulatory Impact Analysis: Barriers and Opportunities.Risk analysis : an official publication of the Society for Risk Analysis · 2021
    Review
  13. Evolving Science and Practice of Risk Assessment.Risk analysis : an official publication of the Society for Risk Analysis · 2021
    Article
  14. Article
  15. Article
  16. A Cumulative Risk Perspective for Occupational Health and Safety (OHS) Professionals.International journal of environmental research and public health · 2020
    Article
  17. Review
  18. State-of-the-Science Review of Non-Chemical Stressors Found in a Child's Social Environment.International journal of environmental research and public health · 2019
    Review
  19. Article
  20. Effects of environmental stressors on stem cells.World journal of stem cells · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ken SextonHuman Genetics & Environmental Sciences, The University of Texas School of Public Health, Brownsville Regional Campus, Brownsville, TX 78520, USA. ken.sexton@uth.tmc.edu
Stephen H Linder
Department of Health Services · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cumulative risk assessment is a science policy tool for organizing and analyzing information to examine, characterize, and possibly quantify combined threats from multiple environmental stressors. We briefly survey the state of the art regarding cumulative risk assessment, emphasizing challenges and complexities of moving beyond the current focus on chemical mixtures to incorporate nonchemical stressors, such as poverty and discrimination, into the assessment paradigm. Theoretical frameworks for integrating nonchemical stressors into cumulative risk assessments are discussed, the impact of geospatial issues on interpreting results of statistical analyses is described, and four assessment methods are used to illustrate the diversity of current approaches. Prospects for future progress depend on adequate research support as well as development and verification of appropriate analytic frameworks.

Indexed as

Environmental ExposureEnvironmental PollutantsHumansRisk AssessmentSocioeconomic FactorsEnvironmental Pollutants

Identifiers

PMID21551386
PMCPMC3222498
OpenAlexW1975061444

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.