ArticleBone2012
Relationship between abdominal fat and bone mineral density in white and African American adults.
Article in Bone, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00959270 (Pennington Center Longitudinal), which is not on this map. Cited by 53 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pennington Center Longitudinal (PCLS)
Who cites it
53 citing papers in PubMed.
- Trial
- Home-based exergaming among children with overweight and obesity: a randomized clinical trial.Pediatric obesity · 2018Trial
- Abdominal fat volume predicts bone mass reduction in women with metabolic syndrome: an energy spectral CT analysis.BMC medical imaging · 2026Article
- GWAS-informed data integration and non-coding CRISPRi screen illuminate genetic etiology of bone mineral density.Genome biology · 2025Article
- Triglycerides-Total Cholesterol-Body Weight Index, bone metabolism indicators and bone mineral density in Chinese children: a mediation analysis.European journal of nutrition · 2025Observational
- Association between Body Composition Characteristics and Bone Mineral Density across Menopausal Transition Stages.Journal of menopausal medicine · 2025Article
- Association of anthropometric and obesity indices with abnormal blood lipid levels in young and middle-aged adults.Heliyon · 2025Article
- Nonlinear relationship between lumbar bone mineral density and high-density lipoprotein cholesterol in patients with type 2 diabetes.Frontiers in endocrinology · 2025Article
- GWAS-Informed data integration and non-coding CRISPRi screen illuminate genetic etiology of bone mineral density.bioRxiv : the preprint server for biology · 2024Article
- Relationship between abdominal fat volume and bone base material pairs from dual-energy spectral computed tomography in young and middle-aged patients with metabolic syndrome.Quantitative imaging in medicine and surgery · 2024Article
- The association between remnant cholesterol and bone mineral density in US adults: the National Health and Nutrition Examination Survey (NHANES) 2013-2018.Lipids in health and disease · 2024Article
- Association between high-density lipoprotein cholesterol and lumbar bone mineral density in Chinese: a large cross-sectional study.Lipids in health and disease · 2024Article
- Obesity and Skeletal Fragility.The Journal of clinical endocrinology and metabolism · 2024Review
- The Usefulness of New Body Indices in Determining the Risk of Cardiovascular Disease in Cases with Obstructive Sleep Apnea Syndrome.International journal of general medicine · 2024Article
- Associations between weight-adjusted waist index and bone mineral density: results of a nationwide survey.BMC endocrine disorders · 2023Article
- Association of visceral and subcutaneous fat with bone mineral density in US adults: a cross-sectional study.Scientific reports · 2023Article
- Associations between weight-adjusted waist index and fractures: a population-based study.Journal of orthopaedic surgery and research · 2023Article
- Opportunistic measures of bone mineral density at multiple skeletal sites during whole-body CT in polytrauma patients.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023Article
- Determinants of bone mass in older adults with normal- and overweight derived from the crosstalk with muscle and adipose tissue.Scientific reports · 2023Article
- Mitochondrial β-oxidation of adipose-derived fatty acids by osteoblasts fuels parathyroid hormone-induced bone formation.JCI insight · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Several studies have documented relationships between adipose tissue and bone mineral density (BMD); however, the degree to which there are racial differences in this relationship is not known. The purpose of this study was to examine the relationships between abdominal visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) and BMD among white and African American adults. The sample included 330 white women, 328 African American women, 307 white men, and 116 African American men 18-74 years of age. Dual-energy X-ray absorptiometry scans were used to measure BMD and computed tomography scans were used to measure abdominal VAT and SAT. Linear regression was used to assess the relationships between abdominal adiposity and BMD and to explore possible sex and race differences in the associations. In the total sample as well as in all sex-by-race groups, VAT and SAT were negatively related to BMD, after adjustment for lean body mass (LBM) and several covariates. The VAT model (including covariates) explained 33.3% of the variance in BMD and the SAT model (including covariates) explained 32.7% of the variance in BMD. Being African American, being male, and having high LBM were all associated with higher BMD. Race and sex interactions were not significant, indicating that the relationships were similar across race and sex groups. In conclusion, BMD was inversely related to abdominal VAT and SAT in white and African American adults after adjustment for LBM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.