Evidence map›Paper›PMID 21549437›Full record

ReviewTrends in biotechnology2011

Micro- and nanoengineering for stem cell biology: the promise with a caution.

Kshitiz, Deok-Ho Kim, David J Beebe, Andre Levchenko

Abstract readReview
In one paragraph

Review in Trends in biotechnology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Review
  2. Article
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  5. Article
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  8. Review
  9. Article
  10. Article
  11. Review
  12. Technology advancement for integrative stem cell analyses.Tissue engineering. Part B, Reviews · 2014
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

KshitizDepartment of Biomedical Engineering, The Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Deok-Ho Kim
David J Beebe
Andre Levchenko

Funding

Analysis and Engineering of Cell Function with Nanoscale CuesR21EB008562 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI LEVCHENKO, ANDRE · 2008 to 2009
$372k
NIBIB NIH HHS R21 EB008562
6 · The paper itself

Abstract

Current techniques used in stem cell research only crudely mimic the physiological complexity of the stem cell niches. Recent advances in the field of micro- and nanoengineering have brought an array of in vitro cell culture models that have enabled development of novel, highly precise and standardized tools that capture physiological details in a single platform, with greater control, consistency, and throughput. In this review, we describe the micro- and nanotechnology-driven modern toolkit for stem cell biologists to design novel experiments in more physiological microenvironments with increased precision and standardization, and caution them against potential challenges that the modern technologies might present.

Indexed as

Stem Cell ResearchAnimalsBioengineeringHumansStem Cells

Identifiers

PMID21549437
PMCPMC3726268

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.