ArticleLab on a chip2011
Miniature magnetic resonance system for point-of-care diagnostics.
Article in Lab on a chip, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it, 150 citations in OpenAlex.
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- Nanomaterials for Molecular Detection and Analysis of Extracellular Vesicles.Nanomaterials (Basel, Switzerland) · 2023Review
- Exosomes as New Generation Vehicles for Drug Delivery: Biomedical Applications and Future Perspectives.Molecules (Basel, Switzerland) · 2022Review
- Advancing microfluidic diagnostic chips into clinical use: a review of current challenges and opportunities.Lab on a chip · 2022Review
- Single-EV analysis (sEVA) of mutated proteins allows detection of stage 1 pancreatic cancer.Science advances · 2022Article
- MPACell reports methods · 2022Article
- A portable NMR platform with arbitrary phase control and temperature compensation.Magnetic resonance (Gottingen, Germany) · 2022Article
- Advances in Biosensors Technology for Detection and Characterization of Extracellular Vesicles.Sensors (Basel, Switzerland) · 2021Review
- Development of Integrated Systems for On-Site Infection Detection.Accounts of chemical research · 2021Review
- A simple, high-throughput method of protein and label removal from extracellular vesicle samples.Nanoscale · 2021Article
- Overhauser dynamic nuclear polarization (ODNP)-enhanced two-dimensional proton NMR spectroscopy at low magnetic fields.Magnetic resonance (Gottingen, Germany) · 2021Article
- Modeling EV Kinetics for Use in Early Cancer Detection.Advanced biosystems · 2020Article
- Cancer Extracellular Vesicles: Next-Generation Diagnostic and Drug Delivery Nanotools.Cancers · 2020Review
- Potential biomarkers and challenges in glioma diagnosis, therapy and prognosis.BMJ neurology open · 2020Review
- Molecular phenotyping of oxidative stress in diabetes mellitus with point-of-care NMR system.NPJ aging and mechanisms of disease · 2020Article
- Structure-Relaxivity Relationships of Magnetic Nanoparticles for Magnetic Resonance Imaging.Advanced materials (Deerfield Beach, Fla.) · 2019Review
- Point-of-care microfluidic devices for pathogen detection.Biosensors & bioelectronics · 2018Review
- Machine learning to detect signatures of disease in liquid biopsies - a user's guide.Lab on a chip · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
We have developed a next generation, miniaturized platform to diagnose disease at the point-of-care using diagnostic magnetic resonance (DMR-3). Utilizing a rapidly growing library of functionalized magnetic nanoparticles, DMR has previously been demonstrated as a versatile tool to quantitatively and rapidly detect disease biomarkers in unprocessed biological samples. A major hurdle for bringing DMR to the point-of-care has been its sensitivity to temperature variation. As an alternative to costly and bulky mechanisms to control temperature, we have implemented an automated feedback system to track and compensate for the temperature drift, which enables reliable and robust DMR measurements in realistic clinical environments (4-50 °C). Furthermore, the new system interfaces with a mobile device to facilitate system control and data sharing over wireless networks. With such features, the DMR-3 platform can function as a self-contained laboratory even in resource-limited, remote settings. The clinical potential of the new system is demonstrated by detecting trace amounts of proteins and as few as 10 bacteria (Staphylococcus aureus) in a short time frame (<30 min).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.