ReviewDeutsches Arzteblatt international2011
Evidence-based treatment of chronic leg ulcers.
Review in Deutsches Arzteblatt international, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Education in people with venous leg ulcers based on a brochure about compression therapy: A quasi-randomised controlled trial.International wound journal · 2019Trial
- Review
- Topical application of cellulose membrane for the treatment of non-healing venous leg ulcers.Frontiers in bioengineering and biotechnology · 2026Article
- Curcumin-Functionalized Ag and ZnO Nanoparticles: A Nanotherapeutic Approach for Treating Infections in Diabetic Wounds.Bioengineering (Basel, Switzerland) · 2025Article
- Allogeneic fibroblasts vs conventional debridement after successful endovascular interventions for treating chronic ulcers induced by peripheral artery disease.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2025Article
- Protein-modified nanomaterials: emerging trends in skin wound healing.Discover nano · 2023Review
- No More Venous Ulcers-What More Can We Do?Journal of clinical medicine · 2023Review
- Clinical and microbiological features of host-bacterial interplay in chronic venous ulcersFrontiers in microbiology · 2023Article
- Pretibial hematomas - A real-world single-center study.JPRAS open · 2022Article
- Wound coverage by the linen dressing accelerates ulcer healing.Postepy dermatologii i alergologii · 2021Article
- New Insights on the Effects of Dietary Omega-3 Fatty Acids on Impaired Skin Healing in Diabetes and Chronic Venous Leg Ulcers.Foods (Basel, Switzerland) · 2021Review
- Chronic Leg Ulcers: Are Tissue Engineering and Biomaterials Science the Solution?Bioengineering (Basel, Switzerland) · 2021Review
- Limb salvage procedure in immunocompromised patients with therapy-resistant leg ulcers-The value of ultra-radical debridement and instillation negative-pressure wound therapy.International wound journal · 2020Article
- Haematological indices of sickle cell patients with chronic leg ulcers on compression therapy.African journal of laboratory medicine · 2020Article
- Contemporary occurrence and aetiology of chronic leg ulcers in Africa: a systematic review and meta-analysis protocol.BMJ open · 2019Article
- Treatment of Nonhealing Ulcers with an Allograft/Xenograft Substitute: A Case Series.Advances in skin & wound care · 2018Observational
- The Management of Critically Colonized and Locally Infected Leg Ulcers with an Acid-Oxidizing Solution: A Pilot Study.Advances in skin & wound care · 2018Article
- [Primary antiphospholipid syndrome: newly developed leg ulcer and history of stroke].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2013Article
- Factors that influence healing of chronic venous leg ulcers: a retrospective cohort.Anais brasileiros de dermatologiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic leg ulcers are defined as those that show no tendency to heal after 3 months of appropriate treatment or are still not fully healed at 12 months. In this article, we present an approach to the challenging problem of chronic leg ulcers that is based on the principles of evidence-based medicine, i.e., the explicit use of the best available scientific evidence as a guide to treatment.
methodsSelective review of the relevant literature, including current guidelines and meta-analyses, concerning diagnostic and therapeutic strategies for chronic leg ulcers.
resultsThe main types of causally directed treatment are: vein surgery to eliminate pathological reflux, interventions to improve the circulation in arterial occlusive disease, and treatment of underlying diseases, such as diabetes mellitus.
conclusionPhysicians providing modern evidence-based management of chronic leg ulcers should make use of their own clinical experience in combination with the best current scientific evidence. It seems clear that the many available treatment options should be evaluated critically in an interdisciplinary setting. In particular, causally directed treatment must be provided in addition to symptomatic, stage-based local wound treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.