ArticleACS medicinal chemistry letters2011
PET Imaging and Biodistribution of Silicon Quantum Dots in Mice.
Article in ACS medicinal chemistry letters, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed.
- In Vivo Assessment of Hepatic and Kidney Toxicity Induced by Silicon Quantum Dots in Mice.Nanomaterials (Basel, Switzerland) · 2024Article
- Nanoparticles labeled with gamma-emitting radioisotopes: an attractive approach for in vivo tracking using SPECT imaging.Drug delivery and translational research · 2023Review
- Recent Developments in Porous Silicon Nanovectors with Various Imaging Modalities in the Framework of Theranostics.ChemMedChem · 2022Review
- Synthesis and Application of Silica-Coated Quantum Dots in Biomedicine.International journal of molecular sciences · 2021Review
- Nano-Bio Interaction between Blood Plasma Proteins and Water-Soluble Silicon Quantum Dots with Enabled Cellular Uptake and Minimal Cytotoxicity.Nanomaterials (Basel, Switzerland) · 2020Article
- Si nanocrystal solution with stability for one year.RSC advances · 2018Article
- Advantages and Limitations of Current Techniques for Analyzing the Biodistribution of Nanoparticles.Frontiers in pharmacology · 2018Review
- Nanometer size silicon particles for hyperpolarized MRI.Scientific reports · 2017Article
- Radiolabeled inorganic nanoparticles for positron emission tomography imaging of cancer: an overview.The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... · 2017Review
- Positron emission tomography and nanotechnology: A dynamic duo for cancer theranostics.Advanced drug delivery reviews · 2017Review
- EPR and Structural Characterization of Water-Soluble MnThe journal of physical chemistry. C, Nanomaterials and interfaces · 2017Article
- Agglomeration of Luminescent Porous Silicon Nanoparticles in Colloidal Solutions.Nanoscale research letters · 2016Article
- Radiolabeled theranostics: magnetic and gold nanoparticles.BioImpacts : BI · 2016Review
- Polymeric Nanostructures for Imaging and Therapy.Chemical reviews · 2015Review
- Nuclear molecular imaging with nanoparticles: radiochemistry, applications and translation.The British journal of radiology · 2015Review
- Quantitative assessment of binding affinities for nanoparticles targeted to vulnerable plaque.Bioconjugate chemistry · 2015Article
- Radiolabeling of Nanoparticles and Polymers for PET Imaging.Pharmaceuticals (Basel, Switzerland) · 2014Article
- Molecular imaging of EGFR/HER2 cancer biomarkers by protein MRI contrast agents.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2014Review
- Multimodality PET/MRI agents targeted to activated macrophages.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2014Article
- Multifunctional nanomedicines: potentials and prospects.Drug delivery and translational research · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Investigation of nanomaterial disposition and fate in the body is critical before such material can be translated into clinical application. Herein a new macrocyclic ligand-(64)Cu(2+) complex was synthesized and used to label dextran-coated silicon quantum dots (QD), with an average hydrodynamic diameter of 15.1 ± 7.6 nm. The chelate showed exceptional stability, demonstrated by no loss radiolabel under a ligand competition reaction with EDTA. The QDs' biodistribution in mice was quantitatively evaluated by in vivo positron emission tomography (PET) imaging and ex vivo gamma counting. Results showed that they were excreted via renal filtration shortly postinjection and also accumulated in the liver.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.