Evidence map›Paper›PMID 21545782›Full record

SynthesisClinical psychology review2011

A meta-analysis of treatments for perinatal depression.

Laura E Sockol, C Neill Epperson, Jacques P Barber

2 registry-linked trialsOpen access · greenAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Clinical psychology review, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 103 papers, 17 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed, 17 pooled it
20.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03351465 nawithdrawnnot on this mapstarted 2020, after this paper: background citation

A Randomized Controlled Trial of Coordinated Anxiety Learning and Management (CALM) for Pregnant and Postpartum Women

TypeinterventionalSponsorUniversity of California, Los AngelesRan2020 to 2020Enrolled0ConditionsAnxiety, Depression, Depression, Postpartum, Pregnancy RelatedArmsCoordinated Anxiety Learning and Management
NCT04495166 nacompletednot on this mapstarted 2020, after this paper: background citation

Smartphone-Assisted Brief Behavioral Intervention for Pregnant Women With Depression

TypeinterventionalSponsorUniversity of Sao PauloRan2020 to 2021Enrolled81ConditionsPerinatal DepressionArmsMotherly 1.0, Brief Psychotherapy, Educational app
3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 17 syntheses or guidelines pooled it, 291 citations in OpenAlex.

  1. Pooled it
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  5. Listening Visits for maternal depression: a meta-analysis.Archives of women's mental health · 2021
    Pooled it
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  8. Interpersonal Psychotherapy to Reduce Psychological Distress in Perinatal Women: A Systematic Review.International journal of environmental research and public health · 2020
    Pooled it
  9. Prenatal Attachment and Perinatal Depression: A Systematic Review.International journal of environmental research and public health · 2020
    Pooled it
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  18. Trial
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43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Laura E SockolDepartment of Psychology, University of Pennsylvania, United States. lsockol@sas.upenn.edu
C Neill Epperson
Jacques P Barber
University of Pennsylvania · US

Funding

Neuroendocrine Contribution to Behavior & Cognition in the Female LifespanK24DA030301 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI EPPERSON, C. NEILL · 2010 to 2014
$954k
NIDA NIH HHS K24 DA030301
6 · The paper itself

Abstract

This meta-analysis assessed efficacy of pharmacologic and psychological interventions for treatment of perinatal depression. A systematic review identified 27 studies, including open trials (n=9), quasi-randomized trials (n=2), and randomized controlled trials (n=16) assessing change from pretreatment to posttreatment or comparing these interventions to a control group. Uncontrolled and controlled effect sizes were assessed in separate meta-analyses. There was significant improvement in depressive symptoms from pretreatment to posttreatment, with an uncontrolled overall effect size (Hedges' g) of 1.61 after removal of outliers and correction for publication bias. Symptom levels at posttreatment were below cutoff levels indicative of clinically significant symptoms. At posttreatment, intervention groups demonstrated significantly greater reductions in depressive symptoms compared to control groups, with an overall controlled effect size (Hedges' g) of 0.65 after removal of outliers. Individual psychotherapy was superior to group psychotherapy with regard to changes in symptoms from pretreatment to posttreatment. Interventions including an interpersonal therapy component were found to have greater effect sizes, compared to control conditions, than interventions including a cognitive-behavioral component. Implications of the findings for clinical practice and future research are discussed.

Indexed as

PsychotherapyAntidepressive AgentsDepression, PostpartumDepressive DisorderFemaleHumansPeripartum PeriodTreatment OutcomeAntidepressive Agents

Identifiers

PMID21545782
PMCPMC4108991
OpenAlexW2005817233

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.