Evidence map›Paper›PMID 21544519›Full record

ReviewEuropean journal of pediatrics2011

Educational paper: primary antibody deficiencies.

Gertjan Driessen, Mirjam van der Burg

Abstract readReview
In one paragraph

Review in European journal of pediatrics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Acupuncture improves immunity and fatigue after chemotherapy in breast cancer patients by inhibiting the Leptin/AMPK signaling pathway.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Overview of Immunodeficiency Disorders.Immunology and allergy clinics of North America · 2015
    Review
  9. Article
  10. Article
  11. Article
  12. [Humoral immunodeficiency : awareness for better support].The Pan African medical journal · 2014
    Review
  13. [Primary immunodeficiency].Zeitschrift fur Rheumatologie · 2013
    Article
  14. Article
  15. Article
  16. Bronchiectasis.Tuberculosis and respiratory diseases · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Gertjan DriessenDivision of Oncology, Center for Childhood Cancer Research, Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA. g.driessen@erasmusmc.nl
Mirjam van der Burg

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary antibody deficiencies (PADs) are the most common primary immunodeficiencies and are characterized by a defect in the production of normal amounts of antigen-specific antibodies. PADs represent a heterogeneous spectrum of conditions, ranging from often asymptomatic selective IgA and IgG subclass deficiencies to the severe congenital agammaglobulinemias, in which the antibody production of all immunoglobulin isotypes is severely decreased. Apart from recurrent respiratory tract infections, PADs are associated with a wide range of other clinical complications. This review will describe the pathophysiology, diagnosis, and treatment of the different PADs.

Indexed as

AgammaglobulinemiaIgA DeficiencyIgG DeficiencyAntibodiesChildDiagnosis, DifferentialHumansRespiratory Tract InfectionsTreatment OutcomeAntibodies

Identifiers

PMID21544519
PMCPMC3098982

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.