Evidence map›Paper›PMID 21544267›Full record

ArticleSoft matter2010

Viscosity and interfacial properties in a mussel-inspired adhesive coacervate.

Dong Soo Hwang, Hongbo Zeng, Aasheesh Srivastava, Daniel V Krogstad, Matthew Tirrell, Jacob N Israelachvili, J Herbert Waite

Abstract read
In one paragraph

Article in Soft matter, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed.

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  12. Single-Molecular Dissection of Liquid-Liquid Phase Transitions.Journal of the American Chemical Society · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dong Soo HwangMaterials Research Laboratory, University of California, Santa Barbara, California, 93106, USA. dshwang@mrl.ucsb.edu; ; Tel: +1-805-893-5787.
Hongbo Zeng
Aasheesh Srivastava
Daniel V Krogstad
Matthew Tirrell
Jacob N Israelachvili
J Herbert Waite

Funding

Translating Mussel AdhesionR01DE018468 · NIDCR · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI WAITE, JOHN HERBERT · 2008 to 2017
$4.2M
NIDCR NIH HHS R01 DE018468
6 · The paper itself

Abstract

The chemistry of mussel adhesion has commanded the focus of much recent research activity on wet adhesion. By comparison, the equally critical adhesive processing by marine organisms has been little examined. Using a mussel-inspired coacervate formed by mixing a recombinant mussel adhesive protein (fp-151-RGD) with hyaluronic acid (HA), we have examined the nanostructure, viscosity, friction, and interfacial energy of fluid-fluid phase-separated coacervates using the surface forces apparatus and microscopic techniques. At mixing ratios of fp-151-RGD:HA resulting in marginal coacervation, the coacervates showed shear-thickening viscosity and no structure by cryo-transmission electron microscopy (cryo-TEM). However, at the mixing ratio producing maximum coacervation, the coacervate showed shear-thinning viscosity and a transition to a bicontinuous phase by cryo-TEM. The shear-thinning viscosity, high friction coefficient (>1.2), and low interfacial energy (<1 mJ m(-2)) observed at the optimal mixing ratio for coacervation are promising delivery, spreading and adhesion properties for future wet adhesive and coating technologies.

Identifiers

PMID21544267
PMCPMC3085400

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.