Evidence map›Paper›PMID 21544001›Full record

ArticleMedical care2011

Health utilities for children and adults with type 1 diabetes.

Joyce M Lee, Kirsten Rhee, Michael J O'grady, Anirban Basu, Aaron Winn, Priya John, David O Meltzer, Craig Kollman, Lori M Laffel, Jean M Lawrence and 5 more

Abstract read
In one paragraph

Article in Medical care, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  15. The Impact of Diabetes-Related Complications on Preference-Based Measures of Health-Related Quality of Life in Adults with Type I Diabetes.Medical decision making : an international journal of the Society for Medical Decision Making · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Joyce M LeePediatric Endocrinology, Child Health Evaluation and Research (CHEAR) Unit, University of Michigan, Ann Arbor, MI 48109-5456, USA. joyclee@umich.edu
Kirsten Rhee
Michael J O'grady
Anirban Basu
Aaron Winn
Priya John
David O Meltzer
Craig Kollman
Lori M Laffel
Jean M Lawrence
William V Tamborlane
Tim Wysocki
Dongyuan Xing
Elbert S Huang
JDRF Continuous Glucose Monitoring Study Group

Funding

Research BaseP30DK092926 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARY ELLEN MICHELE HEISLER, ADESUWA B OLOMU · 2011 to 2026
$10.0M
Research Design, Data, and Analytics CoreP30DK092949 · NIDDK · UNIVERSITY OF CHICAGO · PI MARSHALL H CHIN · 2011 to 2026
$10.0M
Childhood Obesity and Type 2 Diabetes Trends: A Life Course AnalysisK08DK082386 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LEE, JOYCE · 2008 to 2012
$755k
NIDDK NIH HHS K08 DK082386NIDDK NIH HHS P30 DK092926NIDDK NIH HHS P30 DK092949
6 · The paper itself

Abstract

objectiveWe studied health utilities in patients with type 1 diabetes to understand potential differences in health utilities as function of age, type of respondent (self report vs. proxy report), and method of assessment (direct vs. indirect). RESEARCH DESIGN AND

methodsWe elicited self-reported health utilities for adults (n=213) and children (n=238) with type 1 diabetes, and by parent proxy report (n=223) for overall quality of life [Health Utilities Index (HUI) Mark 3 and experienced time-trade-off (TTO) questions] and hypothetical complication states (TTO questions).

resultsMean health utilities for overall quality of life (QOL) ranged from 0.81 to 0.91. Children had significantly higher overall QOL compared with adults (0.89 vs. 0.85, P<0.01) by HUI, but had no significant difference in QOL by TTO. There were no significant differences in QOL between child self report and parent proxy report. Utilities were higher for HUI versus TTO for parent proxy report (P<0.01) but not for adult or child self report. Utilities for hypothetical complication states were lower than for current QOL. Values were lower for stroke (0.34 to 0.53), end stage renal disease (0.47 to 0.55), and blindness (0.52 to 0.69) than for amputation (0.73 to 0.82) and angina (0.74 to 0.80). Complication utilities for parent proxy report were higher compared with adult self report for most hypothetical complication states.

conclusionsIndividuals with type 1 diabetes with few complications report a relatively high QOL; however, future end stage complications are rated as having a significant impact on QOL. Differences in utilities by age, self report versus proxy report, and method raise important questions about whose utilities should be used in economic analyses.

Indexed as

Health Status IndicatorsQuality of LifeAdolescentAdultChildCost-Benefit AnalysisDiabetes Mellitus, Type 1FemaleHumansInterviews as TopicMaleProxyReproducibility of ResultsSurveys and QuestionnairesUnited States

Identifiers

PMID21544001
PMCPMC3210197

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.