ReviewProceedings of the American Thoracic Society2011
Advances in proteomic strategies toward the early detection of lung cancer.
Review in Proceedings of the American Thoracic Society, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Guideline
- Metabolic biomarkers in lung cancer screening and early diagnosis (Review).Oncology letters · 2023Review
- [Role and Significance of Bioactive Substances in Sputum in the Diagnosis of Lung Cancer].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2021Review
- Detection of early lung cancer among military personnel (DECAMP) consortium: study protocols.BMC pulmonary medicine · 2019Article
- The Airway Transcriptome as a Biomarker for Early Lung Cancer Detection.Clinical cancer research : an official journal of the American Association for Cancer Research · 2018Review
- Normalization of mass spectrometry data (NOMAD).Advances in biological regulation · 2018Article
- Development of a test to identify bladder cancer in the urine of patients using mass spectroscopy and subcellular localization of the detected proteins.American journal of translational research · 2015Article
- Review
- The use of quantitative proteomics towards biomarker discovery in lung squamous cell carcinoma.Translational lung cancer research · 2013Article
- Research status and funding trends of lung cancer biomarkers.Journal of thoracic disease · 2013Review
- Review
- The expression and function of microRNA-203 in lung cancer.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2013Article
- The state of molecular biomarkers for the early detection of lung cancer.Cancer prevention research (Philadelphia, Pa.) · 2012Review
- [Proteome profiling for the identification of lung cancer signatures].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2012Article
- Identification of candidate biomarkers for early detection of human lung squamous cell cancer by quantitative proteomics.Molecular & cellular proteomics : MCP · 2012Article
- Clinical proteomics and OMICS clues useful in translational medicine research.Proteome science · 2012Article
- Relevant phosphoproteomic and mass spectrometry: approaches useful in clinical research.Clinical and translational medicine · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Since the advent of the new proteomics era more than a decade ago, large-scale studies of protein profiling have been exploited to identify the distinctive molecular signatures in a wide array of biological systems spanning areas of basic biological research, various disease states, and biomarker discovery directed toward therapeutic applications. Recent advances in protein separation and identification techniques have significantly improved proteomics approaches, leading to enhancement of the depth and breadth of proteome coverage. Proteomic signatures specific for invasive lung cancer and preinvasive lesions have begun to emerge. In this review we provide a critical assessment of the state of recent advances in proteomic approaches and the biological lessons they have yielded, with specific emphasis on the discovery of biomarker signatures for the early detection of lung cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.