ArticleJournal of translational medicine2011
Cancer stem cell subsets and their relationships.
Article in Journal of translational medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The trial behind it
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Who cites it
17 citing papers in PubMed.
- Rewiring Cellular Context as A Central Mechanism Governing Cancer Stem Cell Survival: Insights from ESC Comparisons.Stem cell reviews and reports · 2026Review
- Elemental biomapping of human tissues suggests toxic metals such as mercury play a role in the pathogenesis of cancer.Frontiers in oncology · 2024Article
- Glutamine Metabolism in Cancer Stem Cells: A Complex Liaison in the Tumor Microenvironment.International journal of molecular sciences · 2023Review
- Metabolic Plasticity in Ovarian Cancer Stem Cells.Cancers · 2020Article
- miR-26b enhances radiosensitivity of hepatocellular carcinoma cells by targeting EphA2.Iranian journal of basic medical sciences · 2016Article
- Stem cell technology in breast cancer: current status and potential applications.Stem cells and cloning : advances and applications · 2016Review
- Apoptotic and autophagic pathways with relevant small-molecule compounds, in cancer stem cells.Cell proliferation · 2015Review
- Therapeutic targeting of CBP/β-catenin signaling reduces cancer stem-like population and synergistically suppresses growth of EBV-positive nasopharyngeal carcinoma cells with cisplatin.Scientific reports · 2015Article
- Prognostic value of ALDH1 expression in lung cancer: a meta-analysis.International journal of clinical and experimental medicine · 2015Article
- The crossroads between cancer stem cells and aging.BMC cancer · 2015Review
- Chemotherapy targeting cancer stem cells.American journal of cancer research · 2015Review
- An overview of the role of cancer stem cells in spine tumors with a special focus on chordoma.World journal of stem cells · 2014Review
- Regulation of miRNA processing and miRNA mediated gene repression in cancer.MicroRNA (Shariqah, United Arab Emirates) · 2014Article
- Cell surface markers of cancer stem cells: diagnostic macromolecules and targets for drug delivery.Drug delivery and translational research · 2013Article
- Pilot study on "pericytic mimicry" and potential embryonic/stem cell properties of angiotropic melanoma cells interacting with the abluminal vascular surface.Cancer microenvironment : official journal of the International Cancer Microenvironment Society · 2013Article
- Optimizing molecular-targeted therapies in ovarian cancer: the renewed surge of interest in ovarian cancer biomarkers and cell signaling pathways.Journal of oncology · 2012Article
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Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Emerging evidence suggests that cancer stem cells account for the initiation and progression of cancer. While many types of cancer stem cells with specific markers have been isolated and identified, a variety of differences among them began to be appreciated. Cancer stem cells are hierarchical populations that consist of precancerous stem cells, primary cancer stem cells, migrating cancer stem cells and chemoradioresistant cancer stem cells, playing different roles in cancer initiation and progression. Here we propose a new concept "horizontal hierarchy of cancer stem cells" to distinguish them from vertical hierarchy cancer stem cells, cancer transient-amplifying cells and cancer differentiated cells, and summarize our current understanding of these subsets of cancer stem cells with the aim to open up novel therapeutic strategies for cancer based on this understanding.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.