Evidence map›Paper›PMID 21541197›Full record

ReviewJournal of biomedicine & biotechnology2011

Immunologic monitoring of cellular responses by dendritic/tumor cell fusion vaccines.

Shigeo Koido, Sadamu Homma, Akitaka Takahara, Yoshihisa Namiki, Hideo Komita, Eijiro Nagasaki, Masaki Ito, Keisuke Nagatsuma, Kan Uchiyama, Kenichi Satoh and 3 more

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of biomedicine & biotechnology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 2 countries.

Shigeo KoidoDivision of Gastroenterology and Hepatology, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan. shigeo_koido@jikei.ac.jp
Sadamu Homma
Akitaka Takahara
Yoshihisa Namiki
Hideo Komita
Eijiro Nagasaki
Masaki Ito
Keisuke Nagatsuma
Kan Uchiyama
Kenichi Satoh
Toshifumi Ohkusa
Jianlin Gong
Hisao Tajiri
Jikei University School of Medicine · JPBoston University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although dendritic cell (DC)- based cancer vaccines induce effective antitumor activities in murine models, only limited therapeutic results have been obtained in clinical trials. As cancer vaccines induce antitumor activities by eliciting or modifying immune responses in patients with cancer, the Response Evaluation Criteria in Solid Tumors (RECIST) and WHO criteria, designed to detect early effects of cytotoxic chemotherapy in solid tumors, may not provide a complete assessment of cancer vaccines. The problem may, in part, be resolved by carrying out immunologic cellular monitoring, which is one prerequisite for rational development of cancer vaccines. In this review, we will discuss immunologic monitoring of cellular responses for the evaluation of cancer vaccines including fusions of DC and whole tumor cell.

Indexed as

AnimalsCancer VaccinesCell FusionDendritic CellsHumansMonitoring, ImmunologicNeoplasmsT-LymphocytesCancer Vaccines

Identifiers

PMID21541197
PMCPMC3085507
OpenAlexW2019359880

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.