Evidence map›Paper›PMID 21540858›Full record

ArticleBritish journal of cancer2011

Occupational exposure to dusts and risk of renal cell carcinoma.

S Karami, P Boffetta, P S Stewart, P Brennan, D Zaridze, V Matveev, V Janout, H Kollarova, V Bencko, M Navratilova and 7 more

Open access · hybridAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in British journal of cancer, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Canadian Urological Association guideline for followup of patients after treatment of non-metastatic renal cell carcinoma.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2018
    Article
  3. Article
  4. Article
  5. Renal cell carcinoma: links and risks.International journal of nephrology and renovascular disease · 2016
    Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 4 countries.

S KaramiDivision of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Occupational and Environmental Epidemiology Branch, 6120 Executive Boulevard, EPS 8121, Rockville, MD 20852, USA. karamis@mail.nih.gov
P Boffetta
P S Stewart
P Brennan
D Zaridze
V Matveev
V Janout
H Kollarova
V Bencko
M Navratilova
N Szeszenia-Dabrowska
D Mates
J Gromiec
A Slamova
W-H Chow
N Rothman
L E Moore
United States Department of Health and Human Services · USCentre International de Recherche sur le Cancer · FRCharles University · CZNofer Institute of Occupational Medicine · PLPalacký University Olomouc · CZDivision of Cancer Epidemiology and GeneticsMasaryk Memorial Cancer Institute · CZ

Funding

Studies of Occupational CancerZIACP010120 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI LAN, QING · 2009 to 2025
$34.4M
6 · The paper itself

Abstract

backgroundOccupational exposures to dusts have generally been examined in relation to cancers of the respiratory system and have rarely been examined in relation to other cancers, such as renal cell carcinoma (RCC). Although previous epidemiological studies, though few, have shown certain dusts, such as asbestos, to increase renal cancer risk, the potential for other occupational dust exposures to cause kidney damage and/or cancer may exist. We investigated whether asbestos, as well as 20 other occupational dust exposures, were associated with RCC risk in a large European, multi-center, hospital-based renal case-control study.

methodsGeneral occupational histories and job-specific questionnaires were reviewed by occupational hygienists for subject-specific information. Odds ratios (ORs) and 95% confidence intervals (95% CIs) between RCC risk and exposures were calculated using unconditional logistic regression.

resultsAmong participants ever exposed to dusts, significant associations were observed for glass fibres (OR: 2.1; 95% CI: 1.1-3.9), mineral wool fibres (OR: 2.5; 95% CI: 1.2-5.1), and brick dust (OR: 1.5; 95% CI: 1.0-2.4). Significant trends were also observed with exposure duration and cumulative exposure. No association between RCC risk and asbestos exposure was observed.

conclusionResults suggest that increased RCC risk may be associated with occupational exposure to specific types of dusts. Additional studies are needed to replicate and extend findings.

Indexed as

DustAgedAsbestosCarcinogensCarcinoma, Renal CellCase-Control StudiesEuropeEurope, EasternFemaleGlassHumansKidney NeoplasmsMaleMiddle AgedMineral FibersOccupational DiseasesAsbestosCarcinogensDustfiberglassMineral Fibers

Identifiers

PMID21540858
PMCPMC3111161
OpenAlexW2056736292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.