ArticleThe Plant cell2011
Phloem-specific expression of Yang cycle genes and identification of novel Yang cycle enzymes in Plantago and Arabidopsis.
Article in The Plant cell, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed.
- Metabolomic and Single-Cell Transcriptomic Analyses Shed Light on Secondary Metabolite Profiling and Potential Developmental Dynamics of Glandular Trichomes in Artemisia argyi.Plant biotechnology journal · 2026Article
- Sex-specific ethylene responses drive floral sexual plasticity in Cannabis sativa.The Plant journal : for cell and molecular biology · 2026Article
- Go with the Phloem: A Review of the Methods to Collect Plant Phloem Tissue.Methods in molecular biology (Clifton, N.J.) · 2026Review
- Decoding polyamine-ethylene dynamics: synergies at synthesis and signalling levels during osmotic stress and ripening.Frontiers in plant science · 2026Review
- Decoding Long-Distance Communication Under Mineral Stress: Advances in Vascular Signalling and Molecular Tools for Plant Resilience.Plant, cell & environment · 2025Review
- The Crucial Roles of Phloem Companion Cells in Response to Phosphorus Deficiency.Plant, cell & environment · 2025Article
- Exploring ethylene-related genes in Cannabis sativa: implications for sexual plasticity.Plant reproduction · 2024Article
- Can plant hormonomics be built on simple analysis? A review.Plant methods · 2023Review
- NO Is Not the Same as GSNO in the Regulation of Fe Deficiency Responses by Dicot Plants.International journal of molecular sciences · 2023Review
- Yang cycle enzyme DEP1: its moonlighting functions in PSI and ROS production during leaf senescence.Molecular horticulture · 2022Article
- Maize Interveinal Chlorosis 1 links the Yang Cycle and Fe homeostasis through Nicotianamine biosynthesis.Plant physiology · 2022Article
- Label-free quantitative proteomics of arbuscular mycorrhizalFrontiers in plant science · 2022Article
- Unraveling the Roles of Vascular Proteins Using Proteomics.Molecules (Basel, Switzerland) · 2021Review
- Article
- The regulation of ethylene biosynthesis: a complex multilevel control circuitry.The New phytologist · 2021Review
- RabA2b Overexpression Alters the Plasma-Membrane Proteome and Improves Drought Tolerance in Arabidopsis.Frontiers in plant science · 2021Article
- Metabolism and Regulatory Functions ofFrontiers in plant science · 2021Review
- The basic helix-loop-helix transcription factor MdbHLH3 modulates leaf senescence in apple via the regulation ofHorticulture research · 2020Article
- Boron Deficiency Effects on Sugar, Ionome, and Phytohormone Profiles of Vascular and Non-Vascular Leaf Tissues of Common Plantain (International journal of molecular sciences · 2019Article
- Casein kinase 1 family regulates PRR5 and TOC1 in the Arabidopsis circadian clock.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
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7 authors.
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Abstract
The 5-methylthioadenosine (MTA) or Yang cycle is a set of reactions that recycle MTA to Met. In plants, MTA is a byproduct of polyamine, ethylene, and nicotianamine biosynthesis. Vascular transcriptome analyses revealed phloem-specific expression of the Yang cycle gene 5-METHYLTHIORIBOSE KINASE1 (MTK1) in Plantago major and Arabidopsis thaliana. As Arabidopsis has only a single MTK gene, we hypothesized that the expression of other Yang cycle genes might also be vascular specific. Reporter gene studies and quantitative analyses of mRNA levels for all Yang cycle genes confirmed this hypothesis for Arabidopsis and Plantago. This includes the Yang cycle genes 5-METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE1 and DEHYDRATASE-ENOLASE-PHOSPHATASE-COMPLEX1. We show that these two enzymes are sufficient for the conversion of methylthioribose-1-phosphate to 1,2-dihydroxy-3-keto-5-methylthiopentene. In bacteria, fungi, and animals, the same conversion is catalyzed in three to four separate enzymatic steps. Furthermore, comparative analyses of vascular and nonvascular metabolites identified Met, S-adenosyl Met, and MTA preferentially or almost exclusively in the vascular tissue. Our data represent a comprehensive characterization of the Yang cycle in higher plants and demonstrate that the Yang cycle works primarily in the vasculature. Finally, expression analyses of polyamine biosynthetic genes suggest that the Yang cycle in leaves recycles MTA derived primarily from polyamine biosynthesis.
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