ArticleThe American journal of tropical medicine and hygiene2011
Epidemiology of hookworm infection in Kintampo North Municipality, Ghana: patterns of malaria coinfection, anemia, and albendazole treatment failure.
Article in The American journal of tropical medicine and hygiene, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 5 of them syntheses that pooled it.
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Who cites it
70 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Malaria and helminth co-infections in children living in endemic countries: A systematic review with meta-analysis.PLoS neglected tropical diseases · 2021Pooled it
- The extent, nature, and pathogenic consequences of helminth polyparasitism in humans: A meta-analysis.PLoS neglected tropical diseases · 2019Pooled it
- Plasmodium and intestinal parasite perturbations of the infected host's inflammatory responses: a systematic review.Parasites & vectors · 2018Pooled it
- Water, sanitation, hygiene, and soil-transmitted helminth infection: a systematic review and meta-analysis.PLoS medicine · 2014Pooled it
- Association between footwear use and neglected tropical diseases: a systematic review and meta-analysis.PLoS neglected tropical diseases · 2014Pooled it
- Albendazole Treatment Improves Work Capacity in Women Smallholder Farmers Infected with Hookworm: A Double-Blind Randomized Control Trial.The American journal of tropical medicine and hygiene · 2018Trial
- Cysteine proteinases from papaya (Carica papaya) in the treatment of experimental Trichuris suis infection in pigs: two randomized controlled trials.Parasites & vectors · 2014Trial
- The impact of a school-based hygiene, water quality and sanitation intervention on soil-transmitted helminth reinfection: a cluster-randomized trial.The American journal of tropical medicine and hygiene · 2013Trial
- A 24 month longitudinal cohort study of hookworm infection among school-age children in Ghana: Predictors of persistent and repeated infection.PLoS neglected tropical diseases · 2026Article
- Helminth-infected Mozambican children with malaria have increased anaemia, cytokines and helminth-specific antibodies.PLoS neglected tropical diseases · 2026Article
- Prevalence and predisposing factors of hookworm infection and anemia among pregnant women attending antenatal care in Dawuro Zone, Southwest Ethiopia: an institution-based cross-sectional study.Parasitology research · 2026Article
- Alternative community-based gardening and water banks for micronutrients intake among women in northern Ghana.Dialogues in health · 2025Article
- Adherence to daily food-based dietary recommendations and its association with anemia among Ghanaian women.BMC public health · 2025Article
- Intestinal Parasitic Infections in Ghana: A Review of Infections and the Risk of Zoonotic Transmission.BioMed research international · 2025Review
- The impact of soil transmitted helminth on malaria clinical presentation and treatment outcome: A case control study among children in Bagamoyo district, coastal region of Tanzania.PLoS neglected tropical diseases · 2024Article
- Potential Nutrient Contribution of Community-Based Insects in Children's Food in Northern Ghana.Current developments in nutrition · 2024Article
- Predicting the risk and speed of drug resistance emerging in soil-transmitted helminths during preventive chemotherapy.Nature communications · 2024Article
- Article
- The effect of single dose albendazole (400 mg) treatment on the human gut microbiome of hookworm-infected Ghanaian individuals.Scientific reports · 2023Article
- Determinants of dietary patterns of Ghanaian mother-child dyads: A Demographic and Health Survey.PloS one · 2023Article
10 more citing papers are in PubMed but not listed here.
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A cross-sectional pilot study of hookworm infection was carried out among 292 subjects from 62 households in Kintampo North, Ghana. The overall prevalence of hookworm infection was 45%, peaking in those 11-20 years old (58.5%). In children, risk factors for hookworm infection included coinfection with malaria and increased serum immunoglobulin G reactivity to hookworm secretory antigens. Risk factors for infection in adults included poor nutritional status, not using a latrine, not wearing shoes, and occupation (farming). Although albendazole therapy was associated with an overall egg reduction rate of 82%, 37 subjects (39%) remained infected. Among those who failed therapy, treatment was not associated with a significant reduction in egg excretion, and nearly one-third had higher counts on repeat examination. These data confirm a high prevalence of low-intensity hookworm infection in central Ghana and its association with poor nutritional status. The high rate of albendazole failure raises concern about emerging resistance.
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