Evidence map›Paper›PMID 21540374›Full record

ArticleThe American journal of tropical medicine and hygiene2011

Leishmania (Viannia) infection in the domestic dog in Chaparral, Colombia.

Julián Santaella, Clara B Ocampo, Nancy G Saravia, Fabián Méndez, Rafael Góngora, Maria Adelaida Gomez, Leonard E Munstermann, Rupert J Quinnell

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 40 citations in OpenAlex.

  1. Molecular Detection ofAnimals : an open access journal from MDPI · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Is leishmaniasis the new emerging zoonosis in the world?Veterinary research communications · 2023
    Review
  6. Article
  7. Article
  8. First Report of Canine Infection byInternational journal of environmental research and public health · 2020
    Article
  9. Article
  10. Article
  11. Article
  12. Canine cutaneous leishmaniasis.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2016
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Leishmania (Viannia) guyanensis infection, Austria.Emerging infectious diseases · 2012
    Article
  19. Article
  20. Animal models for the study of leishmaniasis immunology.Revista do Instituto de Medicina Tropical de Sao Paulo
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Julián SantaellaCentro Internacional de Entrenamiento e Investigaciones Médicas, Cali, Colombia. julian.santaella@gmail.com
Clara B Ocampo
Nancy G Saravia
Fabián Méndez
Rafael Góngora
Maria Adelaida Gomez
Leonard E Munstermann
Rupert J Quinnell
Centro Internacional de Entrenamiento e Investigaciones Medicas · CO

Funding

Miltefosine in Pediatric Cutaneous LeishmaniasisU19AI065866 · NIAID · YALE UNIVERSITY · PI MCMAHON PRATT, DIANE · 2005 to 2009
$5.0M
Vector/Host-Parasite Interface of Leishmaniasis in ColombiaD43TW006589 · FIC · YALE UNIVERSITY · PI GORE SARAVIA, NANCY, TSCHUDI, CHRISTIAN · 2003 to 2024
$4.3M
FIC NIH HHS D43 TW006589FIC NIH HHS D43 TW006589-02NIAID NIH HHS U19 AI065866
6 · The paper itself

Abstract

Peridomestic transmission of American cutaneous leishmaniasis is increasingly reported and dogs may be a reservoir of Leishmania (Viannia) in this setting. We investigated the prevalence of infection in dogs in Chaparral County, Colombia, the focus of an epidemic of human cutaneous leishmaniasis caused by Leishmania (Viannia) guyanensis. Two (0.72%) of 279 dogs had lesions typical of cutaneous leishmaniasis that were biopsy positive by kinetoplast DNA polymerase chain reaction-Southern blotting. Seroprevalence was 2.2% (6 of 279) by enzyme-linked immunosorbent assay. Buffy coat and ear skin biopsy specimens were positive by polymerase chain reaction-Southern blotting in 7.3% (10 of 137) and 11.4% (12 of 105) of dogs, respectively. Overall 20% of dogs (21 of 105) showed positive results for one or more tests. Amplification and sequencing of the Leishmania 7SL RNA gene identified L. guyanensis in one dog and L. braziliensis in two dogs. No association was identified between the risk factors evaluated and canine infection. Dogs may contribute to transmission but their role in this focus appears to be limited.

Indexed as

AnimalsBase SequenceColombiaDNA, KinetoplastDNA PrimersDogsEnzyme-Linked Immunosorbent AssayLeishmaniaLeishmaniasisMolecular Sequence DataPolymerase Chain ReactionRisk FactorsSequence Homology, Nucleic AcidSeroepidemiologic StudiesDNA, KinetoplastDNA Primers

Identifiers

PMID21540374
PMCPMC3083732
OpenAlexW2161939488

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.